EPOR cDNA ORF Clone in Cloning Vector, Mouse

Cat: MG50031-M
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EPOR cDNA ORF Clone in Cloning Vector, Mouse General Information
Gene
Species
Mouse
NCBI Ref Seq
RefSeq ORF Size
1524 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Mouse erythropoietin receptor.
Plasmid
Vector
pMD18-T Simple Vector
Sequencing Primers
M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
EPOR cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

EPOR Background Information

Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â…  single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.

Full Name
erythropoietin receptor
References
  • Divoky V, et al. (2002) Mouse surviving solely on human erythropoietin receptor (EpoR): model of human EpoR-linked disease. Blood 99(10): 3873-4.
  • Carruthers SG. (2009) A truncated erythropoietin receptor EPOR-T is associated with hypertension susceptibility. Clin Pharmacol Ther. 86(2): 134-6.
  • Baltaziak M, et al. (2009) Relationships of P53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res. 29(10):4151-6.
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    EPOR cDNA ORF Clone, Human, Related Products

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    EPOR cDNA ORF Clone in Cloning Vector, Human HG13305-G
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    EPOR cDNA ORF Clone, Human, C-His tag HG13305-CH
    EPOR cDNA ORF Clone, Human, N-His tag HG13305-NH
    EPOR cDNA ORF Clone, Human, C-HA tag HG13305-CY
    EPOR cDNA ORF Clone, Human, N-HA tag HG13305-NY
    EPOR cDNA ORF Clone, Human, C-Myc tag HG13305-CM
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