Anti-EPOR Antibody

Cat: 10707-R010
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Anti-EPOR Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-EPOR Antibody
Validated applications
ELISA,ELISA(Det)
Species reactivity
Reacts with: Human
Specificity
Human EPOR
Has cross-reactivity in ELISA with Mouse EPOR
Immunogen
Recombinant Human EPOR Protein (Catalog#10707-H08H)
Preparation
This antibody was obtained from a rabbit immunized with purified, recombinant Human EPOR (rh EPOR; Catalog#10707-H08H; Met 1-Pro 250; NP_000112.1).
Source
Monoclonal Rabbit IgG Clone #010
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-EPOR Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  
ELISA(Det) 1:1000-1:10000 This antibody will detect Human EPOR / Erythropoietin Receptor in ELISA pair set (Catalog: # SEK10707). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10707-R004).

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-EPOR Antibody Alternative Names
Anti-EPO-R Antibody
EPOR Background Information

Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â…  single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.

Full Name
erythropoietin receptor
References
  • Divoky V, et al. (2002) Mouse surviving solely on human erythropoietin receptor (EpoR): model of human EpoR-linked disease. Blood 99(10): 3873-4.
  • Carruthers SG. (2009) A truncated erythropoietin receptor EPOR-T is associated with hypertension susceptibility. Clin Pharmacol Ther. 86(2): 134-6.
  • Baltaziak M, et al. (2009) Relationships of P53 and Bak with EPO and EPOR in human colorectal cancer. Anticancer Res. 29(10):4151-6.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-EPOR Antibody Rabbit Monoclonal ELISA 50031-R140
    Anti-EPOR Antibody Rabbit Polyclonal ELISA 50031-T16
    Anti-EPOR Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 10707-R004
    Anti-EPOR Antibody Rabbit Monoclonal WB 10707-R016
    Anti-EPOR Antibody Rabbit Polyclonal ELISA 10707-RP01
    Anti-EPOR Antibody Mouse Monoclonal ELISA 10707-MM11
    Anti-EPOR Antibody Rabbit Polyclonal ELISA 10707-RP02
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