|ELISA(Det)||1:1000-1:10000||This antibody will detect Human EPOR / Erythropoietin Receptor in ELISA pair set (Catalog: # SEK10707). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 10707-R004).|
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis, and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR/EPO Receptor) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR protein is a type â… single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR signaling prevents neuronal death and ischemic injury. Recent studies have shown that EPO and EPOR protein may be involved in carcinogenesis, angiogenesis, and invasion.
|Product Description||Host||Clonality||Application||Catalog# (PDF)|