ENPP5 Protein

Ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)

ENPP5 Products

ENPP5 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
ENPP5	Human	ENPP5 Protein, Recombinant	11519-H08H

ENPP5 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
ENPP5	Human	Human ENPP5 Gene cDNA Clone / ORF Clone	HG11519-M

ENPP5 Related Areas

Enzyme>>Other>> ENPP5

ENPP5 Alternative Names

UNQ550/PRO1107, KIAA0879, E-NPP 5, NPP-5, ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function), ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [Homo sapiens]

RP23-392N1.1, AW061004, D17Abb1e, E-NPP 5, KIAA4152, mKIAA4152, E-NPP5, NPP-5, ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [Mus musculus]

ENPP5 Background

ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family(NPP). It is a family comprised by dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membrane and hydrolyze extracellular phosphate diesters to affect a wide variety of biological processes. ENPP5 belongs to a group of nucleotidemetabolizing ectoenzymes, which regulate the availability of extracellular nucleotides. ENPP5 may play a role in neuronal cell communication. Hhowever, it lacks nucleotide pyrophosphatase and lysopholipase D activity. It may also be involved in neuronal cell communication. The amino acid sequence of human ENPP5 is 100%, 88%, and 82% identical to that of chimpanzee, dog and mouse/rat. ENPP5 functions in phospholipid metabolism.

ENPP5 Related Studies

1. Strausberg RL, et al. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
2. Gerhard DS, et al. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14(10B):2121-7.
3. Lamesch P, et al. (2007) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics. 89(3):307-15.