All eIF3K reagents are produced in house and quality controlled, including 1 eIF3K Antibody, 30 eIF3K Gene, 1 eIF3K Lysate, 1 eIF3K Protein. All eIF3K reagents are ready to use.
Recombinant eIF3K proteins are expressed by Baculovirus-Insect Cells with fusion tags as N-GST & His.
eIF3Kantibodies are validated with different applications, which are ICC/IF, IF.
eIF3KcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each eIF3K of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: Baculovirus-Insect Cells
EIF3K is a member of the eIF3 subunit K family. It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). It stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. EIF3K is universally expressed in human tissues. It is distributed both in nucleus and cytoplasm. EIF3K is the smallest subunit of eIF3 and it interacts with a number of other subunits of eIF3 and the 40S ribosomal subunit.