EGFR Protein (ErbB, HER1, ErbB1)

Epidermal Growth Factor Receptor

EGFR Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No	Price / Size
EGFR/ErbB/HER1	Human	EGFR/ErbB1/HER1 Protein, Recombinant (Met 1 - Ser 645)	10001-H08H	$130 / 20µg
EGFR/ErbB/HER1	Human	EGFR/ErbB1/HER1/Fc Protein, Recombinant (Met 1 - Ser 645)	10001-H02H	$290 /100µg
EGFR/ErbB/HER1	Human	EGFR/ErbB1/HER1 Protein, Recombinant (Met 1 - Lys 642)	10001-H08B	$350 / 20µg
EGFR/ErbB/HER1	Mouse	EGFR/ErbB1/HER1 Protein, Recombinant	51091-M08H	$290 / 20µg
EGFR/ErbB/HER1	Mouse	EGFR/ErbB1/HER1 Protein, Recombinant	51091-M02H	$290 /100µg
EGFR/ErbB/HER1	Rat	EGFR / HER1 / ErbB1 Protein, Recombinant	80100-R08H	$350 / 20µg

  10001-H08H:  Measure by its ability to bind with human EGF in a functional ELISA.

  10001-H02H: Immobilized recombinant human EGF at 10 μg/mL (100 µl/well) can bind human EGFR with a linear range of 0.64-400 ng/ml. Measured by its binding ability in a functional ELISA.

  10001-H08B:  Immobilized human EGF at 10 µg/mL can bind human EGFR with a linear range of 3.2–400 ng/ml. Measured by its binding ability in a functional ELISA.

EGFR Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No	Price / Size
Human EGFR/ErbB/HER1	WB, ELISA	EGFR / HER1 / ErbB1 Antibody	10001-MM01	$200 / 100µg
Human EGFR/ErbB/HER1	FCM	EGFR / HER1 / ErbB1 Antibody ( FITC )	10001-MM08-F	$200 / 100 Tests
Human EGFR/ErbB/HER1	WB, ELISA	EGFR / HER1 / ErbB1 Antibody	10001-RP01	$190 / 200µg
Human EGFR/ErbB/HER1	WB, ELISA	EGFR / HER1 / ErbB1 Antibody	10001-R021	$290 / 100µg
Human EGFR/ErbB/HER1	WB ELISA IHC-P IHC-Fr IF	EGFR / HER1 / ErbB1 Antibody	10001-R043	$290 / 100µg
Human EGFR/ErbB/HER1	FCM	EGFR / HER1 / ErbB1 Antibody ( FITC )	10001-RE01-F	$200 / 100 Tests

EGFR ELISA Kits

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat No	Price / Size
Human EGFR/ErbB/HER1	ELISA	EGFR / HER1 / ErbB1 ELISA Pair Set, Human ELISA Pair Set	SEK10001	$350 / 5 Plates

EGFR cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No	Price / Size
EGFR/ErbB/HER1	Human	Homo sapiens EGFR/ErbB1/HER1 cDNA Clone	HG10001-C	$395
EGFR/ErbB/HER1	Human	Human EGFR ORF Expression Clone, FLAG-tagged	HG10001-C-F	$395
EGFR/ErbB/HER1	Human	Human EGFR ORF Expression Clone, His-tagged	HG10001-C-H	$395
EGFR/ErbB/HER1	Human	Human EGFR ORF Expression Clone, Myc-tagged	HG10001-C-M	$395
EGFR/ErbB/HER1	Human	Human EGFR ORF Expression Clone, untagged	HG10001-C-N	$395
EGFR/ErbB/HER1	Human	Human EGFR ORF Expression Clone, HA-tagged	HG10001-C-Y	$395
EGFR/ErbB/HER1	Mouse	Mouse EGFR Gene cDNA Clone / ORF Clone	MG51091-G	$395
EGFR/ErbB/HER1	Mouse	Mouse EGFR ORF Expression Clone, FLAG-tagged	MG51091-G-F	$645
EGFR/ErbB/HER1	Mouse	Mouse EGFR ORF Expression Clone, His-tagged	MG51091-G-H	$645
EGFR/ErbB/HER1	Mouse	Mouse EGFR ORF Expression Clone, Myc-tagged	MG51091-G-M	$645
EGFR/ErbB/HER1	Mouse	Mouse EGFR ORF Expression Clone, untagged	MG51091-G-N	$645
EGFR/ErbB/HER1	Mouse	Mouse EGFR ORF Expression Clone, HA-tagged	MG51091-G-Y	$645
EGFR/ErbB/HER1	Canine	Canine EGFR Gene cDNA Clone / ORF Clone	DG70026-G	$395
EGFR/ErbB/HER1	Rat	Rat EGFR/ErbB1/HER1 cDNA Clone	RG80100-G	$395

All EGFR Protein and Antibody

EGFR Alternative Names

EGFR, ERBB, ERBB1, HER1, PIG61, mENA [Homo sapiens]

Egfr, Erbb, RP23-295E4.1, 9030024J15Rik, AI552599, Errp, Wa5, wa-2, wa2 [Mus musculus]

Egfr, ERBB1, ErbB-1, Errp [Rattus norvegicus]

EGFR Related Areas

Enzyme>>Protein Kinase>>Receptor Tyrosine Kinase>>EGFR/ErbB/HER1

Signal Transduction>>Protein Kinase>>Receptor Tyrosine Kinase>>EGFR/ErbB/HER1

Cancer>>Cancer Stem Cell (CSC)>>EGFR/ErbB/HER1

Cancer>>Cancer Biomarkers>>EGFR/ErbB/HER1

Cancer>>Growth Factor & Receptor>>EGF Family & Receptor>>EGFR/ErbB/HER1

Cancer>>Growth Factor & Receptor>>Receptor Tyrosine Kinase>>EGFR/ErbB/HER1

EGFR Protein Related Products

Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
HER2/ErbB2	Human	HER2/ErbB2/Fc Protein, Recombinant
HER2/ErbB2	Human	HER2/ErbB2 Protein, Recombinant
HER2/ErbB2	Mouse	HER2/ErbB2 Protein, Recombinant
HER2	Rat	HER2/Fc Protein, Recombinant
HER2	Rat	HER2 Protein, Recombinant
HER2	Rat	HER2 Protein, Recombinant
HER2	Rhesus	HER2/Fc Protein, Recombinant
HER2	Rhesus	HER2 Protein, Recombinant
HER3	Human	HER3/Fc Protein, Recombinant
HER3	Human	HER3 Protein, Recombinant
HER4	Human	HER4/Fc Protein, Recombinant
EGF	Human	EGF/Fc Protein, Recombinant
EGF	Human	EGF Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human HER2	ELISA	Mouse Monoclonal Antibody
Human HER2	ELISA	Mouse Monoclonal Antibody (Biotin conjugated)
Human HER2	WB	Mouse Monoclonal Antibody (Biotin conjugated)
Human HER2	WB, ELISA, Flow Cytometry	HER2/ErbB2 Antibody, Rabbit MAb
Human HER2	WB, ELISA, IHC, Flow Cytometry	HER2/ErbB2 Antibody, Rabbit MAb
Human HER2	Flow Cytometry	ErbB2/HER2 Antibody, Rabbit MAb
Human HER2	WB, ELISA	Rabbit Polyclonal Antibody
Human HER2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Human HER3	WB, ELISA	HER3/ErbB3 Antibody, Rabbit PAb
Human HER3	WB, ELISA	HER3/ErbB3 Antibody, Rabbit PAb (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
HER2	Human	Homo sapiens HER2 transcript variant 1 cDNA Clone(NM_004448.2)
HER2	Mouse	Mouse HER2 cDNA Clone / ORF Clone
HER2	Rat	Rat HER2/ErbB2 cDNA Clone / ORF Clone
HER2	Rhesus	Rhesus monkey HER2/ErbB2 cDNA Clone / ORF Clone
HER3	Human	Homo sapiens HER3 transcript variant 1 cDNA Clone(NM_001982.2)
HER4	Human	Homo sapiens HER4 transcript variant JM-a/CVT-2 cDNA Clone(NM_001042599.1)

EGFR Background

As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.

EGFR Related Studies

1. Schlessinger, J. (2000) Cell signaling by receptor tyrosine kinases. Cell 103(2): 211-25.
2. Giaccone, G. (2005) HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy. Ann. Oncol. 16(4): 538-48.
3. Yarden, Y., et al. (2001) Untangling the ErbB signalling network. Nat. Rev. Mol. Cell. Biol. 2(2): 127-37.