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EGFR / HER1 / ErbB1 Antibody, Rabbit PAb

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Human EGFR/ErbB1/HER1 Antibody Product Information
Immunogen:Recombinant Human EGFR / ErbB / HER1 protein (Catalog#10001-H08H)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:Produced in rabbits immunized with purified, recombinant Human EGFR / ErbB / HER1 (rh EGFR / ErbB / HER1; Catalog#10001-H08H; Met 1-Ser 645; NP_005219). Total IgG was purified by Protein A affinity chromatography.
Human EGFR/ErbB1/HER1 Antibody Usage Guide
Specificity:Human EGFR / ErbB / HER1
Application:ELISA

ELISA: 0.5-1.0 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human EGFR / HER1 / ErbB1. The detection limit for Human EGFR / HER1 / ErbB1 is approximately ≤ 0.039 ng/well.

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Other EGFR/ErbB1/HER1 Antibody Products
Reactivity: Human  
Application: ELISA  IHC-P  
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10001-T24-200
10001-T24-50
10001-T24-100
200 µg 
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: B/N  
  • Slide 1
10001-RE10-200
10001-RE10-500
200 µg 
500 µg 
Add to Cart
Reactivity: Human  
Application: ELISA  
    10001-RP02-50
    10001-RP02-100
    10001-RP02-200
    50 µg 
    100 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: B/N  
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    10001-REN01-200
    10001-REN01-500
    200 µg 
    500 µg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  IF  ICC/IF  
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    10001-MM08-50
    10001-MM08-100
    10001-MM08-200
    50 µg 
    100 µg 
    200 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  WB  IP  
    • Slide 1
    • Slide 1
    10001-R021-50
    10001-R021-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10001-MM01-200
      10001-MM01-50
      10001-MM01-100
      200 µg 
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  IHC-P  IF  IHC-Fr  
      • Slide 1
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      10001-R043-50
      10001-R043-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10001-RE01-F-50
      10001-RE01-F-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10001-MM08-F-50
      10001-MM08-F-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10001-MM08-P-50
      10001-MM08-P-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10001-RE01-P-50
      10001-RE01-P-100
      50 Tests 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10001-RE01-100
        10001-RE01-50
        100 µg 
        50 µg 
        Add to Cart
        Reactivity: Human  
        Application: WB  
        • Slide 1
        100372-T32-50
        100372-T32-100
        100372-T32-200
        50 µg 
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10001-RE01-A-100
        10001-RE01-A-50
        100 Tests 
        50 Tests 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10001-MM08-A-100
        10001-MM08-A-50
        100 Tests 
        50 Tests 
        Add to Cart
        Reactivity: Human  
        Application: IHC-P  
        • Slide 1
        • Slide 1
        • Slide 1
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        10001-MM11-100
        10001-MM11-50
        10001-MM11-200
        100 µg 
        50 µg 
        200 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          51091-R112-50
          51091-R112-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            51091-R004-50
            51091-R004-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  WB  IP  
            • Slide 1
            • Slide 1
            51091-T52-200
            51091-T52-50
            51091-T52-100
            200 µg 
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              51091-RP01-200
              51091-RP01-400
              51091-RP01-100
              200 µg 
               
              100 µg 
              Add to Cart
              Reactivity: Rat  
              Application: ELISA  
                80100-RP01-100
                80100-RP01-200
                100 µg 
                200 µg 
                Add to Cart
                Reactivity: Rat  
                Application: ELISA  WB  IP  
                • Slide 1
                • Slide 1
                80100-T52-200
                80100-T52-100
                80100-T52-50
                200 µg 
                100 µg 
                50 µg 
                Add to Cart
                Reactivity: Rhesus  
                Application: ELISA  
                  90317-RP01-200
                  90317-RP01-100
                  90317-RP01-400
                  200 µg 
                  100 µg 
                   
                  Add to Cart
                  Reactivity: Rhesus  
                  Application: ELISA  
                    90317-T16-100
                    90317-T16-200
                    90317-T16-50
                    100 µg 
                    200 µg 
                    50 µg 
                    Add to Cart
                    EGFR/HER1 Background

                    As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.

                    Human EGFR/HER1 References
                  • Schlessinger, J. (2000) Cell signaling by receptor tyrosine kinases. Cell 103(2): 211-25.
                  • Giaccone, G. (2005) HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy. Ann. Oncol. 16(4): 538-48.
                  • Yarden, Y., et al. (2001) Untangling the ErbB signalling network. Nat. Rev. Mol. Cell. Biol. 2(2): 127-37.
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                    Size / Price
                    Catalog: 10001-RP01-400
                    List Price: 
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                    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"