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EGFR/HER1 Rabbit PAb

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    Rat EGFR Antibody Product Information
    Immunogen:Recombinant Rat EGFR / HER1 / ErbB1 protein (Catalog#80100-R08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Rat EGFR / HER1 / ErbB1 (rR EGFR / HER1 / ErbB1; Catalog#80100-R08H; E7CXR8; Met1-Ser646). Total IgG was purified by Protein A affinity chromatography.
    Other EGFR Antibody Products
    Reactivity: Human  
    Application: ELISA  IHC-P  
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    10001-T24-200
    10001-T24-50
    10001-T24-100
    200 µg 
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: B/N  
    • Slide 1
    10001-RE10-200
    10001-RE10-500
    200 µg 
    500 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10001-RP02-50
      10001-RP02-100
      10001-RP02-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: B/N  
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      10001-REN01-200
      10001-REN01-500
      200 µg 
      500 µg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  IF  ICC/IF  
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      10001-MM08-50
      10001-MM08-100
      10001-MM08-200
      50 µg 
      100 µg 
      200 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  WB  IP  
      • Slide 1
      • Slide 1
      10001-R021-50
      10001-R021-100
      50 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        10001-RP01-400
        10001-RP01-100
        10001-RP01-200
         
        100 µg 
        200 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          10001-MM01-200
          10001-MM01-50
          10001-MM01-100
          200 µg 
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  IHC-P  IF  IHC-Fr  
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          10001-R043-50
          10001-R043-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10001-RE01-F-50
          10001-RE01-F-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10001-MM08-F-50
          10001-MM08-F-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10001-MM08-P-50
          10001-MM08-P-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: FCM  
          • Slide 1
          10001-RE01-P-50
          10001-RE01-P-100
          50 Tests 
          100 Tests 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            10001-RE01-100
            10001-RE01-50
            100 µg 
            50 µg 
            Add to Cart
            Reactivity: Human  
            Application: WB  
            • Slide 1
            100372-T32-50
            100372-T32-100
            100372-T32-200
            50 µg 
            100 µg 
            200 µg 
            Add to Cart
            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10001-RE01-A-100
            10001-RE01-A-50
            100 Tests 
            50 Tests 
            Add to Cart
            Reactivity: Human  
            Application: FCM  
            • Slide 1
            10001-MM08-A-100
            10001-MM08-A-50
            100 Tests 
            50 Tests 
            Add to Cart
            Reactivity: Human  
            Application: IHC-P  
            • Slide 1
            • Slide 1
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            • Slide 1
            10001-MM11-100
            10001-MM11-50
            10001-MM11-200
            100 µg 
            50 µg 
            200 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  
              51091-R112-50
              51091-R112-100
              50 µg 
              100 µg 
              Add to Cart
              Reactivity: Mouse  
              Application: ELISA  
                51091-R004-50
                51091-R004-100
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  WB  IP  
                • Slide 1
                • Slide 1
                51091-T52-200
                51091-T52-50
                51091-T52-100
                200 µg 
                50 µg 
                100 µg 
                Add to Cart
                Reactivity: Mouse  
                Application: ELISA  
                  51091-RP01-200
                  51091-RP01-400
                  51091-RP01-100
                  200 µg 
                   
                  100 µg 
                  Add to Cart
                  Reactivity: Rat  
                  Application: ELISA  WB  IP  
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                  80100-T52-200
                  80100-T52-100
                  80100-T52-50
                  200 µg 
                  100 µg 
                  50 µg 
                  Add to Cart
                  Reactivity: Rhesus  
                  Application: ELISA  
                    90317-RP01-200
                    90317-RP01-100
                    90317-RP01-400
                    200 µg 
                    100 µg 
                     
                    Add to Cart
                    Reactivity: Rhesus  
                    Application: ELISA  
                      90317-T16-100
                      90317-T16-200
                      90317-T16-50
                      100 µg 
                      200 µg 
                      50 µg 
                      Add to Cart

                      Anti-Histone H3 rabbit monoclonal antibody at 1:200 dilution

                      Lane A: NIH3T3 Whole Cell Lysate

                      Lane B: Hela Whole Cell Lysate

                      Lysates/proteins at 30 μg per lane.

                      Secondary

                      Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.

                      Developed using the ECL technique.

                      Performed under reducing conditions.

                      Predicted band size:15 kDa

                      Observed band size:17 kDa

                      EGFR/HER1 Background

                      As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.

                      Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

                      Rat EGFR/HER1 References
                    • Schlessinger, J. (2000) Cell signaling by receptor tyrosine kinases. Cell 103(2): 211-25.
                    • Giaccone, G. (2005) HER1/EGFR-targeted agents: predicting the future for patients with unpredictable outcomes to therapy. Ann. Oncol. 16(4): 538-48.
                    • Yarden, Y., et al. (2001) Untangling the ErbB signalling network. Nat. Rev. Mol. Cell. Biol. 2(2): 127-37.
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                      Size / Price
                      Catalog: 80100-RP01-100
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                      200 µg
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                      Datasheet & Documentation

                      All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
                      Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"