Anti-EGF Antibody

Cat: 10605-R008
Contact us:
All EGF Reagents
CRO Services
Product recommended

All EGF Reagents
Anti-EGF Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-EGF Antibody
Validated applications
Species reactivity
Reacts with: Human
Human EGF
Recombinant Human EGF protein (Catalog#10605-HNAE)
This antibody was obtained from a rabbit immunized with purified, recombinant Human EGF(rh EGF; Catalog#10605-HNAE; NP_001954.2; Asn 971-Arg 1023) .
Monoclonal Rabbit IgG Clone #008
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-EGF Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-EGF Antibody Alternative Names
Anti-Epidermal Growth Factor Antibody;Anti-HOMG4 Antibody;Anti-URG Antibody
EGF Background Information

EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. Human EGF is a 6045-Da protein with 53 amino acid residues and three intramolecular disulfide bonds. As a low-molecular-weight polypeptide, EGF was first purified from the mouse submandibular gland, but since then it was found in many human tissues including submandibular gland, parotid gland. It can also be found in human platelets, macrophages, urine, saliva, milk, and plasma. EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. It results in cellular proliferation, differentiation, and survival. Salivary EGF, which seems also regulated by dietary inorganic iodine, also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity. EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.

Full Name
epidermal growth factor
  • Chen JX, et al. (2011) Involvement of c-Src/STAT3 signal in EGF-induced proliferation of rat spermatogonial stem cells. Mol Cell Biochem. 358(1-2):67-73.
  • Guo Y, et al. (2012) Correlations among ERCC1, XPB, UBE2I, EGF, TAL2 and ILF3 revealed by gene signatures of histological subtypes of patients with epithelial ovarian cancer. Oncol Rep. 27(1):286-92.
  • Kim S, et al. (2012) Smad7 acts as a negative regulator of the epidermal growth factor (EGF) signaling pathway in breast cancer cells. Cancer Lett. 314(2):147-54.
  • Chatterton RT Jr, et al. (2010) Breast ductal lavage for assessment of breast cancer biomarkers. Horm Cancer. 1(4):197-204.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-EGF Antibody Mouse Monoclonal ELISA 70013-MM07
    Anti-EGF Antibody Rabbit Polyclonal ELISA 70013-RP01
    Anti-EGF Antibody Rabbit Polyclonal ELISA 80446-RP01
    Anti-EGF Antibody Mouse Monoclonal ELISA 80446-MM02
    Anti-EGF Antibody Rabbit Polyclonal ELISA,IHC-P 80446-T24
    Anti-EGF Antibody Rabbit Monoclonal ELISA 80446-R005
    Anti-EGF Antibody Rabbit Polyclonal ELISA 50482-T16
    Anti-EGF Antibody Rabbit Polyclonal WB 101619-T32
    Anti-EGF Antibody Rabbit Polyclonal ELISA 10605-T16
    Anti-EGF Antibody Rabbit Monoclonal Neutralization 10605-R001
    Anti-EGF Antibody Rabbit Polyclonal ELISA 10605-RP01
    info info
    添加购物车成功! 添加购物车失败!