EFNB2A cDNA ORF Clone in Cloning Vector, Danio rerio (zebrafish)

Cat: ZG63002-G
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EFNB2A cDNA ORF Clone in Cloning Vector, Danio rerio (zebrafish) General Information
Gene
Species
Danio rerio (zebrafish)
NCBI Ref Seq
RefSeq ORF Size
999 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Danio rerio (zebrafish) ephrin B2a.
Plasmid
Vector
pGEM-T Vector
Sequencing Primers
SP6 and T7 or M13-47 and RV-M
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Ampicillin
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
EFNB2A cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

EFNB2A cDNA ORF Clone in Cloning Vector, Danio rerio (zebrafish) Alternative Names
efnb2 cDNA ORF Clone, Danio rerio (zebrafish);EFNB2A cDNA ORF Clone, Danio rerio (zebrafish)
EFNB2A Background Information

Efnb2a, also known as ephrin B2a, belongs to the ephrin family. Members of this family are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Efnb2a binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Efnb2a, together with ephb4 may play a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.

References
  • Shaw KM. et al., 2006, Dev Dyn. 235 (7): 1753-60.
  • Kemp HA. et al., 2009, Dev Biol. 327 (2): 313-26.
  • Patten SA. et al., 2012, PLoS One. 7 (2): e31650.
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