Endothelin B Receptor (Protein|Antibody|cDNA Clone|ELISA Kit)
All Endothelin B Receptor reagents are produced in house and quality controlled, including 13 Endothelin B Receptor Gene, 2 Endothelin B Receptor Lysate, 2 Endothelin B Receptor Protein, 1 Endothelin B Receptor qPCR. All Endothelin B Receptor reagents are ready to use.
Recombinant Endothelin B Receptor proteins are expressed by HEK293 Cells with fusion tags as C-mouse IgG1-Fc, C-His.
Endothelin B Receptor cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Endothelin B Receptor of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
The hypermethylation of EDNRB gene was remarkably related to infiltration and metastasis of gastric cancer and may attribute to the tumor progression. EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. Low EDNRB expression played a role in the progression of ACC tumors. The autosomal recessive mutation in EDNRB may underlie a part of WS1 with the current diagnostic criteria, and supported that Hirschsprung's disease is a multifactorial genetic disease which requires additional factors.