Anti-ECM1 Antibody

Cat: 50331-RP02
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All ECM1 Reagents
Anti-ECM1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-ECM1 Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse ECM1
Recombinant Mouse ECM1 protein (Catalog#50331-M08H)
Produced in rabbits immunized with purified, recombinant Mouse ECM1 (rM ECM1; Catalog#50331-M08H; Q61508-1; Met 1-Glu 559). ECM1 specific IgG was purified by Mouse ECM1 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ECM1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-ECM1 Antibody Alternative Names
Anti-AI663821 Antibody;Anti-p85 Antibody
ECM1 Background Information

Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling. 

Full Name
extracellular matrix protein 1
Research Areas
  • Oyama N, et al. (2003) Autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Lancet. 362(9378): 118-23.
  • Chan I, et al. (2004) Rapid diagnosis of lipoid proteinosis using an anti-extracellular matrix protein 1 (ECM1) antibody. J Dermatol Sci. 35(2): 151-3.
  • Lupo I, et al. (2005) A novel mutation of the extracellular matrix protein 1 gene (ECM1) in a patient with lipoid proteinosis (Urbach-Wiethe disease) from Sicily. Br J Dermatol. 153(5): 1019-22.
  • Sander CS, et al. (2006) Expression of extracellular matrix protein 1 (ECM1) in human skin is decreased by age and increased upon ultraviolet exposure. Br J Dermatol. 154(2): 218-24.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-ECM1 Antibody Rabbit Monoclonal ELISA 80574-R101
    Anti-ECM1 Antibody Rabbit Polyclonal ELISA 80574-RP01
    Anti-ECM1 Antibody Rabbit Polyclonal ELISA 80574-T16
    Anti-ECM1 Antibody Rabbit Monoclonal ELISA 50331-R038
    Anti-ECM1 Antibody Rabbit Monoclonal ELISA 50331-R001
    Anti-ECM1 Antibody Rabbit Polyclonal ELISA 50331-RP01
    Anti-ECM1 Antibody Mouse Monoclonal ELISA(Cap) 10362-MM01
    Anti-ECM1 Antibody Rabbit Polyclonal ELISA 10362-T16
    Anti-ECM1 Antibody Rabbit Polyclonal ELISA 10362-RP01
    Anti-ECM1 Antibody Mouse Monoclonal ELISA 10362-MM03
    Anti-ECM1 Antibody Rabbit Monoclonal ELISA 10362-R015
    Anti-ECM1 Antibody Rabbit Monoclonal ELISA(Det) 10362-R030
    Anti-ECM1 Antibody Rabbit Polyclonal ELISA 10362-RP02
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