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DPY30 domain containing 2 Protein Datasheet
DYDC2 Protein Price Inquiry ( Available Sizes )
DYDC2 Protein Product Information
A DNA sequence encoding the mature form of human DYDC2 (Q96IM9) (Thr102-Pro176) was fused with the GST tag at the N-terminus.
DYDC2 Protein QC Testing
|Purity:||> 93 % as determined by SDS-PAGE||SDS-PAGE:
|Endotoxin:||Please contact us for more information.|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Met|
|Molecular Mass:||The recombinant human DYDC2 /GST chimera consists of 307 amino acids and has a predicted molecular mass of 35.5 kDa. It migrates as an approximately 37 KDa band in SDS-PAGE under reducing conditions.|
|Formulation:||Lyophilized from sterile PBS, pH7.4.
DYDC2 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
DYDC2 Protein Related Products & Topics
DYDC2 Protein Description
DPY30 domain containing 2 is a member of the dpy-30 family. Members of this family act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 binds to metal response elements (MREs) and plays a key role in transition metal detoxification and homeostasis. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport.
- Deloukas P. et al., 2004, Nature. 429 (6990): 375-81.
- Rual JF. et al., 2005, Nature. 437 (7062): 1173-8.
- Xin X. et al., 2009, Genome Res. 19 (7): 1262-9.