Anti-DYDC2 Antibody

Cat: 13911-RP01
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Anti-DYDC2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-DYDC2 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human DYDC2
Immunogen
Recombinant Human DYDC2 protein (Catalog#13911-H09E)
Preparation
Produced in rabbits immunized with purified, recombinant Human DYDC2 (rh DYDC2; Catalog#13911-H09E; Q96IM9; Thr102-Pro176). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-DYDC2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

DYDC2 Background Information

DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays a key role in transition metal detoxification and homeostasis. It binds to metal response elements (MREs). Two candidate dMTF-1 interactors are related to the small regulatory protein Dumpy-30 (Dpy-30) of the worm C. elegans. Dpy-30 is the founding member of a protein family involved in chromatin modifications, notably histone methylation. Mutants affect mating type in yeast and male mating in C. elegans. As part of the MLL1/MLL complex, DPY30 domain containing 2 is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. DPY30 domain containing 2 may also play an indirect or direct role in endosomal transport.

Full Name
DPY30 domain containing 2
References
  • 1. Deloukas P, et al. (2004) The DNA sequence and comparative analysis of human chromosome 10. Nature. 429(6990):375-81.
  • 2. Rual JF, et al. (2005) Towards a proteome-scale map of the human protein-protein interaction network. Nature. 437(7062):1173-8.
  • 3. Xin X, et al. (2009) Shifted Transversal Design smart-pooling for high coverage interactome mapping. Genome Res. 19(7):1262-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-DYDC2 Antibody Rabbit Polyclonal ELISA 13911-T16
    Anti-DYDC2 Antibody Rabbit Monoclonal ICC/IF,IF 13911-R101
    Anti-DYDC2 Antibody Mouse Monoclonal ELISA 13911-MM04
    Anti-DYDC2 Antibody Rabbit Monoclonal ELISA 13911-R009
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