Text Size:AAA

DSG2/desmoglein 2  Antibody

All DSG2 Reagents

Reactivity: Human  
Application: WB  IHC-P  IP  
13684-T44-50
13684-T44-200
13684-T44-100
50 µg 
200 µg 
100 µg 
Add to Cart
  • Slide 1
  • Slide 1
  • Slide 1

Browse DSG2/desmoglein 2 Products by

DSG2/desmoglein 2 Related Area

DSG2/desmoglein 2 Related Pathways

    DSG2/desmoglein 2 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    DSG2/desmoglein 2 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    Featured Reagent Products

    DSG2/desmoglein 2 Summary & Protein Information

    DSG2/desmoglein 2 Background

    Domain: Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain. {ECO:0000250}.
    Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
    Tissue specificity: All of the tissues tested and carcinomas.
    Involvement in disease: DISEASE: Arrhythmogenic right ventricular dysplasia, familial, 10 (ARVD10) [MIM:610193]: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias. {ECO:0000269|PubMed:16773573, ECO:0000269|PubMed:19863551, ECO:0000269|PubMed:20031617, ECO:0000269|PubMed:21062920}. Note=The disease is caused by mutations affecting the gene represented in this entry.; DISEASE: Cardiomyopathy, dilated 1BB (CMD1BB) [MIM:612877]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. {ECO:0000269|PubMed:18678517}. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.
    Sequence similarity: Contains 4 cadherin domains. {ECO:0000255|PROSITE-ProRule:PRU00043}.
    General information above from UniProt

    DSG2/desmoglein 2 Alternative Name

    HDGC,CDHF5,ARVC10,ARVD10,CMD1BB, [homo-sapiens]
    AA408168,D18Ertd293e, [mus-musculus]

    DSG2/desmoglein 2 Related Studies

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"