|Recombinant Mouse Dkk3 protein (Catalog#50247-M08H)|
|0.2 μm filtered solution in PBS|
|This antibody was obtained from a rabbit immunized with purified, recombinant Mouse DKK3 (rM DKK3; Catalog#50247-M08H; NP_056629.1; Met 1-Ile 349).|
No cross-reactivity in ELISA with
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse DKK3. The detection limit for Mouse DKK3 is approximately 0.0049 ng/well.
ELISA(Cap): 0.5-4 µg/ml
This antibody will detect Mouse DKK3 in ELISA pair set (Catalog: # SEK50247). In a sandwich ELISA, it can be used as capture antibody.
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.