|ELISA(Cap)||1:250-1:2000||This antibody will detect Mouse DKK3 in ELISA pair set (Catalog: # SEK50247). In a sandwich ELISA, it can be used as capture antibody.|
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.
|Product Description||Host||Clonality||Application||Catalog# (PDF)|