Anti-DKK3 Antibody

Cat: 10203-MM01

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Anti-DKK3 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-DKK3 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human DKK3
Recombinant Human Dkk3 protein (Catalog#10203-H08H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Dkk3 (rhDkk3; Catalog#10203-H08H; aa 1-350; NP_001018067.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #8D5A3E3
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-DKK3 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-DKK3 Antibody Alternative Names
Anti-REIC Antibody;Anti-RIG Antibody
DKK3 Background Information

DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1, DKK2, DKK3 and DKK4. It is a secreted protein, and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

Full Name
dickkopf WNT signaling pathway inhibitor 3
  • Yue W, et al., 2008. Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer. Carcinogenesis, 29 (1): 84-92.
  • Ding Z, et al., 2009. Promoter methylation and mRNA expression of DKK3 and WIF-1 in hepatocellular carcinoma. World J Gastroenterol, 15 (21):2595-601.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-DKK3 Antibody Rabbit Monoclonal ELISA,ELISA(Cap) 50247-R019
    Anti-DKK3 Antibody Rabbit Polyclonal ELISA 50247-RP01
    Anti-DKK3 Antibody Rabbit Polyclonal ELISA,IHC-P 50247-RP02
    Anti-DKK3 Antibody Rabbit Polyclonal ELISA 10203-RP04
    Anti-DKK3 Antibody Rabbit Polyclonal ELISA 10203-RP03
    Anti-DKK3 Antibody Mouse Monoclonal ELISA(Cap) 10203-MM05
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