Anti-DKK1 Antibody

Cat: 10170-RP01
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All DKK1 Reagents
Anti-DKK1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-DKK1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human DKK1
Human cell-derived rhDKK1 (Catalog#10170-H08H)
Produced in rabbits immunized with purified, recombinant Human dickkopf related protein 1 (rhDkk1; Catalog#10170-H08H; NP_036374.1; Met 2-His266). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-DKK1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
WB 1:500-1:1000  
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-DKK1 Antibody (Rabbit Polyclonal antibody) Images
Human DKK1/Dkk-1 Western blot (WB) 13134

Anti-DKK1 rabbit polyclonal antibody at 1:500 dilution

Lane A: Hela Whole Cell Lysate

Lane B: HepG2 Whole Cell Lysate

Lysates/proteins at 30 μg per lane.


Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:29 kDa

Observed band size:53 kDa

Anti-DKK1 Antibody Alternative Names
Anti-DKK-1 Antibody;Anti-SK Antibody
DKK1 Background Information

Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers.

Full Name
dickkopf WNT signaling pathway inhibitor 1
  • Horwitz EM. (2004) Dkk-1-mediated expansion of adult stem cells. Trends Biotechnol. 22(8): 386-8.
  • Jiang T, et al. (2009) Clinical significance of serum DKK-1 in patients with gynecological cancer. Int J Gynecol Cancer. 19(7): 1177-81.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-DKK1 Antibody Rabbit Polyclonal ELISA 11089-RP01
    Anti-DKK1 Antibody Rabbit Polyclonal ELISA 11089-T16
    Anti-DKK1 Antibody Rabbit Polyclonal WB,ELISA 11089-T48
    Anti-DKK1 Antibody Rabbit Monoclonal WB,ELISA 10170-R004
    DKK-1 Neutralizing Antibody Rabbit Monoclonal Neutralization 10170-R015
    Anti-DKK1 Antibody Rabbit Polyclonal WB,ELISA,IP 10170-RP02
    Anti-DKK1 Antibody Rabbit Polyclonal ELISA,IHC-P 10170-T16
    Anti-DKK1 Antibody Mouse Monoclonal ELISA,ELISA(Det) 10170-MM03
    Anti-DKK1 Antibody Mouse Monoclonal ELISA(Cap) 10170-MM08
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