CLEC4A (Protein|Antibody|cDNA Clone|ELISA Kit)

All CLEC4A reagents are produced in house and quality controlled, including 9 CLEC4A Antibody, 2 CLEC4A ELISA, 13 CLEC4A Gene, 1 CLEC4A Lysate, 1 CLEC4A Protein, 1 CLEC4A qPCR. All CLEC4A reagents are ready to use.

Recombinant CLEC4A proteins are expressed by HEK293 Cells with fusion tags as N-His.

CLEC4Aantibodies are validated with different applications, which are IHC-P, FCM, ELISA, ELISA(Cap), ELISA(Det).

CLEC4AcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CLEC4A of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

CLEC4AELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

CLEC4A Protein (1)

Species

CLEC4A Protein, Human, Recombinant (His Tag)

11476-H07H

Expression host: HEK293 Cells

Human DCIR/CLEC4A/CLECSF6 Protein 9584
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CLEC4A Antibody (9)

Application Clonality
Host

Anti-CLEC4A Antibody

11476-MM04

Application: ELISA,ELISA(Cap)

Clonality: MAb

Anti-CLEC4A Antibody

11476-MM08

Application: ELISA,FCM

Clonality: MAb

Human DCIR/CLEC4A/CLECSF6 Flow Cytometry (FC) 5209

Anti-CLEC4A Antibody (FITC)

11476-MM08-F

Application: FCM

Clonality: MAb

Human DCIR/CLEC4A/CLECSF6 Flow Cytometry (FC) 5404

Anti-CLEC4A Antibody (PE)

11476-MM08-P

Application: FCM

Clonality: MAb

Human DCIR/CLEC4A/CLECSF6 Flow Cytometry (FC) 5404

Anti-CLEC4A Antibody

11476-R007

Application: ELISA

Clonality: MAb

Anti-CLEC4A Antibody

11476-RP02

Application: ELISA

Clonality: PAb

Anti-CLEC4A Antibody

11476-MM02

Application: ELISA,ELISA(Det)

Clonality: MAb

Anti-CLEC4A Antibody

11476-RP01

Application: ELISA

Clonality: PAb

Anti-CLEC4A Antibody

11476-MM06

Application: IHC-P

Clonality: MAb

Human DCIR/CLEC4A/CLECSF6 Immunohistochemistry(IHC) 4397
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CLEC4A ELISA KIT & match antibody elias pair set ( 2 )

CLEC4A ELISA Kit, Human

KIT11476

Sensitivity: 13.18 pg/mL

Human DCIR/CLEC4A/CLECSF6 ELISA Kit Standard Curve 104

CLEC4A Matched ELISA Antibody Pair Set,Human

SEK11476

Assay Range: 9.375 pg/ml

Human DCIR/CLEC4A/CLECSF6 ELISA Pair Set Standard Curve 13929

CLEC4A cDNA Clone (13)

Human

CLEC4A qPCR Primer (1)

CLEC4A Lysate (1)

Dendritic cell immunoreceptor (DCIR), also known as C-type lectin domain family 4 member A (CLEC4A), C-type lectin superfamily member 6 (CLECSF6), is a single-pass type II C-type lectin receptor expressed mainly in dendritic cells (DCs), which is a negative regulator of DC expansion and has a crucial role in maintaining the homeostasis of the immune system. The Dectin-2 family of C-type lectins that includes Dectin-2, BDCA-2, DCIR, DCAR, Clecsf8 and Mincle. These type II receptors contain a single extracellular carbohydrate recognition domain and have diverse functions in both immunity and homeostasis. DCIR is the only member of the family which contains a cytoplasmic signalling motif and has been shown to act as an inhibitory receptor, while BDCA-2, Dectin-2, DCAR and Mincle all associate with FcRgamma chain to induce cellular activation, including phagocytosis and cytokine production. Dectin-2 and Mincle have been shown to act as pattern recognition receptors for fungi, while DCIR acts as an attachment factor for HIV. In addition to pathogen recognition, DCIR has been shown to be pivotal in preventing autoimmune disease by controlling dendritic cell proliferation. DCIR expressed on antigen presenting cells and granulocytes and acts as an inhibitory receptor via an intracellular immunoreceptor tyrosine-based inhibitory motif (ITIM). It may also be involved via its ITIM motif in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation. Additionally, DCIR can participate in the capture of HIV-1 and promote infection in trans and in cis of autologous CD4(+) T cells from human immature monocyte-derived DCs. DCIR acts as a ligand for HIV-1 and is involved in events leading to productive virus infection.

Protein
Antibody
ELISA
Gene
qPCR
Lysate
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