Anti-Cystatin SA Antibody

Cat: 11567-RP02
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Anti-Cystatin SA Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Cystatin SA Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Cystatin SA
Immunogen
Recombinant Human CST2 protein (Catalog#11567-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human CST2 (rh CST2; Catalog#11567-H08H; NP_001313.1; Met 1-Ala 141). CST2 specific IgG was purified by human CST2 affinity chromatography .
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Cystatin SA Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Cystatin SA Antibody Alternative Names
Anti-CST2 Antibody;Anti-MGC71924 Antibody
Cystatin SA Background Information

Cystatin-SA, also known as Cystatin-2, Cystatin-S5 and CST2, is a secreted protein which belongs to the cystatin family. Cystatin-2 / CST2 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). It is also expressed in submandibular gland and parotid gland. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The CST1, CST2, CST4, and CST5 are expressed in differential, tissue-specific patterns. Expression of CST2 and CST5 is restricted to the submandibular and parotid glands, while CST1 and CST4 are expressed in these tissues and in the lacrimal gland.

Full Name
cystatin SA
References
  • Saitoh E., et al.,(1987), Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family. Gene 61:329-338.
  • Zhang Z., et al., (2004), Signal peptide prediction based on analysis of experimentally verified cleavage sites.Protein Sci. 13:2819-2824.
  • Deloukas P., et al.,(2001), The DNA sequence and comparative analysis of human chromosome 20.Nature 414:865-871.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Cystatin SA Antibody Rabbit Polyclonal ELISA 11567-RP01
    Anti-Cystatin SA Antibody Rabbit Monoclonal ELISA(Cap) 11567-R005
    Anti-Cystatin SA Antibody Rabbit Polyclonal ELISA 11567-T16
    Anti-Cystatin SA Antibody Rabbit Monoclonal ELISA,ELISA(Det) 11567-R016
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