Anti-Cystatin F Antibody

Cat: 10167-RP02
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Anti-Cystatin F Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Cystatin F Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human Cystatin F
Immunogen
Recombinant Human CST7 protein (Catalog#10167-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human CST7 (rh CST7; Catalog#10167-H08H; NP_003641.2; Met 1-His 145). CST7 specific IgG was purified by human CST7 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Cystatin F Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Cystatin F Antibody Alternative Names
Anti-CMAP Antibody
Cystatin F Background Information

The cystatin superfamily members are important natural cysteine protease inhibitors present in a wide variety of organisms and are divided into three classes. Cystatin F, also known as leukocystatin and CMAP (Cystatin-like Metastasis-Associated Protein), is a type 2 cystatin and its expression is limited to hematopoietic cells, with the highest expression levels being observed in monocytes, dendritic cells, and certain types of T-cells. Furthermore, cystatin F mRNA becomes up-regulated during dendritic cell maturation, and thus suggests a specific role of cystatin F in immune regulation. Cystatin F is produced as a dimer, an inactive cathepsin inhibitor which is activated by chemical reduction. In addition, Cystatin F and its homologues have been observed expressing in various human cancer cell lines established from malignant tumors, and thus indicates a new diagnosis and prevention approach of certain human carcinomas metastasis.

Full Name
cystatin F (leukocystatin)
References
  • Halfon S., et al.,(1998), Leukocystatin, a new class II cystatin expressed selectively by hematopoietic cells. J. Biol. Chem. 273:16400-16408.
  • Ni J., et al., (1998), Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor.J. Biol. Chem. 273:24797-24804.
  • Morita M., et al.,(2000), Genomic construct and mapping of the gene for CMAP (leukocystatin/cystatin F, CST7) and identification of a proximal novel gene, BSCv (C20orf3).Genomics 67:87-91.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Cystatin F Antibody Rabbit Polyclonal ELISA 50236-RP01
    Anti-Cystatin F Antibody Rabbit Polyclonal ELISA 50236-T16
    Anti-Cystatin F Antibody Mouse Monoclonal ELISA 10167-MM04
    Anti-Cystatin F Antibody Mouse Monoclonal WB 10167-MM01
    Anti-Cystatin F Antibody Rabbit Polyclonal ELISA 10167-RP01
    Anti-Cystatin F Antibody Rabbit Polyclonal WB 10167-T32
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