Anti-CST6 Antibody

Cat: 10438-RP02
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All CST6 Reagents
Anti-CST6 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-CST6 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human CST6
Recombinant Human CST6 protein (Catalog#10438-H08H)
Produced in rabbits immunized with purified, recombinant Human Cystatin-M / CST6 (rh Cystatin-M; Catalog#10438-H08H; NP_001314.1; Met 1-Met 149). CST6 specific IgG was purified by human CST6 affinity chromatography .
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CST6 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

CST6 Background Information

Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene.

Full Name
cystatin E/M
  • Ritonja A., et al.,(1985), Amino acid sequence of the intracellular cysteine proteinase inhibitor cystatin B from human liver. Biochem. Biophys. Res. Commun. 131:1187-1192.
  • Pennacchio L.A., et al., (1996), Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPM1).Science 271:1731-1734.
  • Ghaemmaghami S., et al.,(2003), Global analysis of protein expression in yeast.Nature 425:737-741.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CST6 Antibody Rabbit Polyclonal ELISA,IHC-P 50916-RP02
    Anti-CST6 Antibody Rabbit Polyclonal ELISA 50916-RP01
    Anti-CST6 Antibody Rabbit Monoclonal ELISA 50916-R037
    Anti-CST6 Antibody Mouse Monoclonal IHC-P 10438-MM17
    Anti-CST6 Antibody Rabbit Monoclonal ELISA 10438-R034
    Anti-CST6 Antibody Mouse Monoclonal ELISA,ELISA(Det) 10438-MM02
    Anti-CST6 Antibody Rabbit Monoclonal ELISA(Cap) 10438-R022
    Anti-CST6 Antibody Mouse Monoclonal ELISA 10438-MM19
    Anti-CST6 Antibody Rabbit Polyclonal ELISA 10438-RP01
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