All Cystatin C reagents are produced in house and quality controlled, including 14 Cystatin C Antibody, 2 Cystatin C ELISA, 39 Cystatin C Gene, 2 Cystatin C IPKit, 4 Cystatin C Lysate, 4 Cystatin C Protein, 3 Cystatin C qPCR. All Cystatin C reagents are ready to use.
Recombinant Cystatin C proteins are expressed by HEK293 Cells with fusion tags as Native, C-His.
Cystatin Cantibodies are validated with different applications, which are ELISA, WB, IP, IHC-P, ELISA(Det), ELISA(Cap).
Cystatin CcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Cystatin C of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Cystatin CELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. The mature, active form of human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues, with a molecular mass of 13,343-13,359 Da, and containing four characteristic disulfide-paired cysteine residues. Cystatin C is a low-molecular-weight protein which has been proposed as a marker of renal function that could replace creatinine. Indeed, the concentration of Cystatin C is mainly determined by glomerular filtration and is particularly of interest in clinical settings where the relationship between creatinine production and muscle mass impairs the clinical performance of creatinine. Since the last decade, numerous studies have evaluated its potential use in measuring renal function in various populations. More recently, other potential developments for its clinical use have emerged. In almost all the clinical studies, Cystatin C demonstrated a better diagnostic accuracy than serum creatinine in discriminating normal from impaired kidney function, but controversial results have been obtained by comparing this protein with other indices of kidney disease, especially serum creatinine-based equations, such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. Cystatin C could be a useful clinical tool to identify HIV-infected persons. In addition, its expression is up-regulated in malignance of certain tumor progression.