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Cystatin A / CSTA Antibody, Rabbit PAb

  • Cystatin A / CSTA Antibody, Rabbit PAb, Immunohistochemistry
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Human Cystatin A/CSTA Antibody Product Information
Immunogen:Recombinant Human Cystatin A / CSTA protein (Catalog#10479-H07E)
Clone ID:
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:Produced in rabbits immunized with purified, recombinant Human Cystatin A / CSTA (rh Cystatin A / CSTA; Catalog#10479-H07E; P01040; Ile 2-Phe 98). Total IgG was purified by Protein A affinity chromatography.
Human Cystatin A/CSTA Antibody IHC Application Image
Cystatin A / CSTA Antibody, Rabbit PAb, Immunohistochemistry
[Click to enlarge image]
Caption:
Immunochemical staining of human CSTA in human tonsil with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
Other Cystatin A/CSTA Antibody Products
Cystatin A / CSTA Background

Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to the cystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is located mainly in the keratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epidermis. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family).

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Catalog: 10479-RP01-400
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Datasheet & Documentation

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"