Anti-Cyclophilin A Antibody

Cat: 50296-R001
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All Cyclophilin A Reagents
Anti-Cyclophilin A Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-Cyclophilin A Antibody
Validated applications
Species reactivity
Reacts with: Mouse
Mouse Cyclophilin A
Recombinant Mouse PPIA protein (Catalog#50296-M08E)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse PPIA (rM PPIA; Catalog#50296-M08E; NP_032933.1; Met 1-Leu 164) .
Monoclonal Rabbit IgG Clone #001
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Cyclophilin A Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Cyclophilin A Antibody Alternative Names
Anti-2700098C05 Antibody;Anti-Cphn Antibody;Anti-CyP-18 Antibody;Anti-CypA Antibody
Cyclophilin A Background Information

Peptidyl-prolyl cis-trans isomerase A, also known as PPIase A, Rotamase A, Cyclophilin A, Cyclosporin A-binding protein, PPIA and CYPA, is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. Cyclophilins (CyPs) are a family of proteins found in organisms ranging from prokaryotes to humans. These molecules exhibit peptidyl-prolyl isomerase activity, suggesting that they influence the conformation of proteins in cells. PPIA / Cyclophilin A accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli, and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. PPIA / Cyclophilin A can interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.

Full Name
peptidylprolyl isomerase A (cyclophilin A)
  • Haendler B., et al.,(1987), Complementary DNA for human T-cell cyclophilin. EMBO J. 6:947-950.
  • Haendler B., et al., (1990), Characterization of the human cyclophilin gene and of related processed pseudogenes.Eur. J. Biochem. 190:477-482.
  • Ota T., et al.,(2004), Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36:40-45.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Cyclophilin A Antibody Rabbit Polyclonal ELISA 50296-RP02
    Anti-Cyclophilin A Antibody Rabbit Polyclonal WB,ELISA,IP 10436-T52
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