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Cyclin A1 Protein & Antibody (CCNA1)

Cyclin A1

Cyclin A1 Products

Cyclin A1 Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Cyclin A1/CCNA1 Human Cyclin A1/CCNA1 Protein, Recombinant 11013-H07B

Cyclin A1 Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
Cyclin A1/CCNA1
WB, ELISA Cyclin A1/CCNA1 Antibody, Mouse MAb 11013-MM02
Human
Cyclin A1/CCNA1
WB, ELISA Cyclin A1 / CCNA1 Antibody 11013-RP01

Cyclin A1 cDNA Clone

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Cyclin A1/CCNA1 Human Homo sapiens Cyclin A1/CCNA1 cDNA Clone HG11013-M

Cyclin A1 Related Areas

Cancer>>Cell Cycle>>Cyclin>>Cyclin A1/CCNA1

Cyclin A1 Alternative Names

CCNA1, cyclin-A1 [Homo sapiens]

Ccna1, MGC159139, cyclin-A1 [Mus musculus]

Cyclin A1 Background

Cyclin A1 is a member of the highly conserved cyclin family that is characterized by a dramatic periodicity in protein abundance, and belongs to the A-type cyclin subfamily. The mammalian A-type cyclin family consists of two members: cyclin A1 and cyclin A2. Different cyclins exhibit distinct expression. Cyclin A1 is expressed in mice exclusively in the germ cell lineage and high rate of cyclinA1 is found in human testis and certain myeloid leukaemia cells. Cyclin A1 is primarily function in the control of meiosis. It serves as regulator subunits binding to cyclin-dependent kinase 1 (Cdk1) and cyclin-dependent kinase 2 (Cdk2), which give two different kinase activities, one appearing in S phase, the other in G2. Through this, cyclin A1 operate the entry and progression in cell cycle. High frequency of cyclin A1 overexpression has been observed in acute myelocytic leukemias, especially those that are at the promyelocyte and myeloblast stages of development.

Cyclin A1 Related Studies

  1. Yang R, et al. (1999) Functions of Cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins. Molecular and Cellular biology. 19 (3): 2400-7.
  2. Yang R, et al. (1999) Cyclin A1 expression in leukemia and normal hematopoietic cells. Blood. 93 (6): 2067-74.

 

Cyclin A1 related areas, pathways, and other information

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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