Anti-Cyclin A1 Antibody (PE)

Cat: 11013-MM02-P
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All Cyclin A1 Reagents
CRO Services

All Cyclin A1 Reagents
Anti-Cyclin A1 Antibody (PE) (Mouse Monoclonal antibody) General Information
Product name
Anti-Cyclin A1 Antibody (PE)
Validated applications
FCM
Species reactivity
Reacts with: Human
Specificity
Human Cyclin A1
Immunogen
Recombinant Human Cyclin A1 / CCNA1 protein (Catalog#11013-H07B)
Preparation
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cyclin A1 / CCNA1 (rh Cyclin A1 / CCNA1; Catalog#11013-H07B; NP_003905.1; Met1-Gln465) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Source
Monoclonal Mouse IgG2a Clone #02
Purification
Protein A
Formulation
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
Conjugate
PE
Concentration
10 μl/Test, 0.1 mg/ml
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-Cyclin A1 Antibody (PE) (Mouse Monoclonal antibody) Validated Applications

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Cyclin A1 Antibody (PE) (Mouse Monoclonal antibody) Images
Human Cyclin A1/CCNA1 Flow Cytometry (FC) 4853
Human CCNA1 expression in HeLa cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with PE Mouse anti-CCNA1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Anti-Cyclin A1 Antibody (PE) Alternative Names
Anti-CT146 Antibody
Cyclin A1 Background Information

Cyclin A1 is a member of the highly conserved cyclin family that is characterized by a dramatic periodicity in protein abundance, and belongs to the A-type cyclin subfamily. The mammalian A-type cyclin family consists of two members: cyclin A1 and cyclin A2. Different cyclins exhibit distinct expression. Cyclin A1 is expressed in mice exclusively in the germ cell lineage and high rate of cyclinA1 is found in human testis and certain myeloid leukaemia cells. Cyclin A1 is primarily function in the control of meiosis. It serves as regulator subunits binding to cyclin-dependent kinase 1 (Cdk1) and cyclin-dependent kinase 2 (Cdk2), which give two different kinase activities, one appearing in S phase, the other in G2. Through this, cyclin A1 operate the entry and progression in cell cycle. High frequency of cyclin A1 overexpression has been observed in acute myelocytic leukemias, especially those that are at the promyelocyte and myeloblast stages of development.

Full Name
cyclin A1
References
  • Yang R, et al. (1999) Functions of Cyclin A1 in the cell cycle and its interactions with transcription factor E2F-1 and the Rb family of proteins. Molecular and Cellular biology. 19 (3): 2400-7.
  • Yang R, et al. (1999) Cyclin A1 expression in leukemia and normal hematopoietic cells. Blood. 93 (6): 2067-74.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Cyclin A1 Antibody Mouse Monoclonal WB,ELISA,ICC/IF,IF 11013-MM02
    Anti-Cyclin A1 Antibody Rabbit Polyclonal ELISA 11013-RP01
    Anti-Cyclin A1 Antibody Mouse Monoclonal FCM,ICC/IF,IF 11013-MM06
    Anti-Cyclin A1 Antibody Mouse Monoclonal IHC-P 11013-MM01
    Anti-Cyclin A1 Antibody Rabbit Polyclonal WB,ELISA,IP 11013-T52
    Anti-Cyclin A1 Antibody (PE) Mouse Monoclonal FCM 11013-MM06-P
    info info
    添加购物车成功! 添加购物车失败!