Contactin 5 / CNTN5 Protein & Antibody

Contactin 5 / CNTN5 Products

Contactin 5 / CNTN5 Protein, Recombinant

Molecule	Species	Description	Cat. No
Contactin 5/CNTN5/NB-2	Human	Contactin 5/CNTN5 Protein, Recombinant	10513-H08H

  10513-H08H: When 5 x 10⁴ cells/well are added to CNTN5 coated plates (0.8 µg/mL and 100 µL/well), approximately 30%-50% will adhere specifically after 60 minutes at 37℃. Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells.

Contactin 5 / CNTN5 Antibody

Molecule	Application	Description	Cat. No
Human Contactin 5/CNTN5/NB-2	WB, ELISA	Mouse Monoclonal Antibody	10513-MM02
Human Contactin 5/CNTN5/NB-2	ELISA	Mouse Monoclonal Antibody	10513-MM11
Human Contactin 5/CNTN5/NB-2	WB, ELISA	Contactin 5/CNTN5/NB-2 Antibody, Rabbit MAb	10513-R121
Human Contactin 5/CNTN5/NB-2	WB, ELISA	Rabbit Polyclonal Antibody	10513-RP01
Human Contactin 5/CNTN5/NB-2	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)	10513-RP02

Contactin 5 / CNTN5 cDNA Clone

Molecule	Species	Description	Cat. No
Contactin 5/CNTN5/NB-2	Human	Homo sapiens Contactin 5/CNTN5 cDNA Clone(NM_014361.2)	HG10513-M
Contactin 5/CNTN5/NB-2	Mouse	CNTN5 cDNA Clone / ORF Clone	MG51092-G
Contactin 5/CNTN5/NB-2	Rat	CNTN5 cDNA Clone / ORF Clone	RG80409-G

Contactin 5 / CNTN5 Related Areas

Immunology>>Adhesion Molecule>>Cell Adhesion Molecule (IgSF CAM)>>Contactin 5/CNTN5

Contactin 5 / CNTN5 Alternative Names

Contactin 5, CNTN5, NB-2, HNB-2s, MGC163491 [Homo sapiens]

Contactin 5, Cntn5, NB-2, 6720426O10Rik, A830025P08Rik, Gm507 [Mus musculus]

Contactin 5 / CNTN5 Related Products

Protein Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
Contactin 1/CNTN1	Human	Contactin 1/CNTN1 Protein, Recombinant
Contactin 2/CNTN2/TAG1	Human	Contactin 2/CNTN2/TAG-1 Protein, Recombinant
Contactin 3/CNTN3	Human	Contactin 3/CNTN3/Fc Protein, Recombinant
Contactin 3/CNTN3	Human	Contactin 3/CNTN3 Protein, Recombinant

Antibody Products

Molecule	Application	Description //For Detailed Info. and Price------CLICK!
Human Contactin 1/CNTN1	WB, ELISA	Mouse Monoclonal Antibody
Human Contactin 2/CNTN2/TAG1	WB, ELISA	Mouse Monoclonal Antibody
Human Contactin 2/CNTN2/TAG1	ELISA	Rabbit Polyclonal Antibody
Human Contactin 2/CNTN2/TAG1	WB, ELISA	Rabbit Polyclonal Antibody(Antigen Affinity Purified)
Human Contactin 3/CNTN3	WB, ELISA	Mouse Monoclonal Antibody
Human Contactin 3/CNTN3	WB, ELISA	Contactin 3/CNTN3 Antibody, Rabbit MAb
Human Contactin 3/CNTN3	WB, ELISA	Rabbit Polyclonal Antibody
Human Contactin 3/CNTN3	WB, ELISA	Rabbit Polyclonal Antibody (Antigen Affinity Purified)

cDNA Clone Products

Molecule	Species	Description //For Detailed Info. and Price------CLICK!
Contactin 1/CNTN1	Human	Homo sapiens Contactin 1/CNTN1 transcript variant 1 cDNA Clone(NM_001843.2)
Contactin 2/CNTN2/TAG1	Human	Homo sapiens Contactin 2/CNTN2/TAG-1 cDNA Clone(NM_005076.2)
Contactin 3/CNTN3	Human	Homo sapiens Contactin 3/CNTN3 cDNA Clone(NM_020872.1)
Contactin 4/CNTN4	Human	Homo sapiens Contactin 4/CNTN4 transcript variant 1 cDNA Clone(NM_175607.1)
Contactin 4/CNTN4	Mouse	Mus musculus Contactin 4/CNTN4 cDNA Clone

Contactin 5 / CNTN5 Background

Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed mainly in the nervous system. The subgroup consists of six members: Contactin-1, Contactin-2(TAG-1), Contactin-3(BIG-1), BIG-2, Contactin-5(NB-2) and NB-3. Since their identification in the late 1980s, Contactin-1 and Contactin-2 have been studied extensively. Axonal expression and the neurite extension activity of Contactin-1 and Contactin-2 attracted researchers to study the function of these molecules in axon guidance during development. Contactin-1 and Contactin-2 have come to be known as the principal molecules in the function and maintenance of myelinated neurons. In contrast, the function of the other four members of this subgroup remained unknown until recently. Contactin-5, also known as NB-2, is one of the neural recognition molecules in the contactin subgroup. Contactin-5 is expressed in brain and kidney and at very low level in placenta. In brain, Contactin-5 is highly expressed in the occipital lobe, amygdala, cerebral cortex, frontal lobe, thalamus and temporal lobe. Mice deficient in the Contactin-5 gene exhibit aberrant responses to acoustic stimuli. Contactin-5 may play a role in maturation of glutamatergic synapses in the brainstem during the final stages of auditory development. Contactin-5 gene may contribute to human neurological disorders.

Contactin 5 / CNTN5 Related Studies

1. Kamei Y, et al. (2000) Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members. Genomics 69(1):113-9.
2. Ogawa J, et al. (2001) Neural recognition molecule NB-2 of the contactin/F3 subgroup in rat: Specificity in neurite outgrowth-promoting activity and restricted expression in the brain regions. J Neurosci Res. 65(2):100-10.
3. Li H, et al. (2003) Aberrant responses to acoustic stimuli in mice deficient for neural recognition molecule NB-2. Eur J Neurosci. 17(5):929-36.
4. Shimoda Y, et al. (2009) Contactins: Emerging key roles in the development and function of the nervous system. Cell adhesion & migration 3(1):64-70.
5. Toyoshima M, et al. (2009) Preferential localization of neural cell recognition molecule NB-2 in developing glutamatergic neurons in the rat auditory brainstem. J Comp Neurol. 513(4):349-62.