C2 (Protein|Antibody|cDNA Clone|ELISA Kit)

All C2 reagents are produced in house and quality controlled, including 3 C2 Antibody, 2 C2 ELISA, 26 C2 Gene, 3 C2 Lysate, 3 C2 Protein, 1 C2 qPCR. All C2 reagents are ready to use.

Recombinant C2 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc, C-His.

C2antibodies are validated with different applications, which are ELISA, ELISA(Det), ELISA(Cap).

C2cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each C2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

C2ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.

C2 Protein (3)

Species

C2 Protein, Human, Recombinant (His Tag)

10154-H08H

Expression host: HEK293 Cells

Human Complement Component C2 Protein 8457

C2 Protein, Human, Recombinant (Fc Tag)

10154-H02H

Expression host: HEK293 Cells

Human Complement Component C2 Protein 8456

C2 Protein, Mouse, Recombinant (His Tag)

51140-M08H

Expression host: HEK293 Cells

Mouse Complement Component C2 Protein 12120
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C2 Antibody (3)

Application Clonality
Host

Anti-C2 Antibody

10154-R014

Application: ELISA(Cap)

Clonality: MAb

Anti-C2 Antibody

10154-MM06

Application: ELISA(Det)

Clonality: MAb

Anti-C2 Antibody

10154-R002

Application: ELISA

Clonality: MAb

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C2 ELISA KIT & match antibody elias pair set ( 2 )

C2 ELISA Kit, Human

KIT10154

Sensitivity: 110.77 pg/mL

Human Complement Component C2 ELISA Kit Standard Curve 40

C2 Matched ELISA Antibody Pair Set,Human

SEK10154

Assay Range: 78.125 pg/ml

Human Complement Component C2 ELISA Pair Set Standard Curve 13794

C2 cDNA Clone (26)

Mouse
Human

C2 qPCR Primer (1)

C2 Lysate (3)

Complement component C2 is part of the classical complement pathway which plays a major role in innate immunity against infection. C2 is a glycoprotein synthesized in liver hepatocytes and several other cell types in extrahepatic tissues. This pathway is triggered by a multimolecular complex C1, and subsequently the single-chain form of C2 is cleaved into two chains referred to C2a and C2b by activated C1. The second component of complement (C2) is a multi-domain serine protease that provides catalytic activity for the C3 and C5 convertases of the classical and lectin pathways of human complement. C4b and C2 was investigated by surface plasmon resonance. C2a containing a serine protease domain combines with complement component C4b to form the C3 convertase C4b2a which is responsible for C3 activation, and leads to the stimulation of adaptive immune responses via Lectin pathway. C2 bound to C4b is cleaved by classical (C1s) or lectin (MASP2) proteases to produce C4bC2a. C2 has the same serine protease domain as C4bC2a but in an inactive zymogen-like conformation, requiring cofactor-induced conformational change for activity. Deficiency of C2 (C2D) is the most common genetic deficiency of the complement system, and two types of C2D have been recognized in the context of specific MHC haplotypes. C2D in human is reported to increase susceptibility to infection, and is associated with certain autoimmune diseases, such as rheumatological disorders.

Protein
Antibody
ELISA
Gene
qPCR
Lysate
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