Clusterin Protein & Antibody (Apolipoprotein J, Apo-J Protein)

Clusterin Products

Clusterin Protein, Recombinant

Molecule	Species	Description	Cat. No
Clusterin/Apolipoprotein J/Apo-J	Human	Clusterin/Apolipoprotein J/Apo-J Protein, Recombinant	11297-H08H
Clusterin/Apolipoprotein J/Apo-J	Mouse	Clusterin/Apolipoprotein J/Apo-J Protein, Recombinant	50485-M08H

Clusterin Antibody

Molecule	Application	Description	Cat. No
Human Clusterin/Apolipoprotein J/Apo-J	WB, ELISA	Clusterin / Apolipoprotein J / Apo-J Antibody	11297-MM01
Human Clusterin/Apolipoprotein J/Apo-J	WB, ELISA	Clusterin / Apolipoprotein J / Apo-J Antibody	11297-RP01
Human Clusterin/Apolipoprotein J/Apo-J	WB, ELISA	Clusterin / Apolipoprotein J / Apo-J Antibody (Antigen Affinity Purified)	11297-RP02
Mouse Clusterin/Apolipoprotein J/Apo-J	WB, ELISA	Clusterin / Apolipoprotein J / Apo-J / CLU Antibody	50485-RP01
Mouse Clusterin/Apolipoprotein J/Apo-J	WB, ELISA	Clusterin / Apolipoprotein J / Apo-J / CLU Antibody (Antigen Affinity Purified)	50485-RP02

Clusterin cDNA Clone

Molecule	Species	Description	Cat. No
Clusterin/Apolipoprotein J/Apo-J	Human	Homo sapiens Clusterin/Apolipoprotein J/Apo-J cDNA Clone	HG11297-M
Clusterin/Apolipoprotein J/Apo-J	Mouse	Mus musculus Clusterin/Apolipoprotein J/Apo-J cDNA Clone	MG50485-M

Clusterin Related Areas

Cardiovascular>>Lipid Metabolism>>Clusterin/Apolipoprotein J/Apo-J

Clusterin Alternative Names

Clusterin, CLU, apo-J, apolipoprotein J, AAG4, APOJ, CLI, KUB1, MGC24903, SGP-2, SGP2, SP-40, TRPM-2, TRPM2, NA1/NA2, aging-associated protein 4, complement cytolysis inhibitor, complement lysis inhibitor [Homo sapiens]

Clusterin, Clu, Apolipoprotein J, apo-J, AI893575, ApoJ, Cli, D14Ucla3, SP-40, Sgp-2, Sgp2, Sugp-2, clustrin, complement lysis inhibitor, sulfated glycoprotein 2 [Mus musculus]

Clusterin Background

Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

Clusterin Related Studies

1. Silkensen JR, et al. (1994) The role of clusterin in tissue injury. Biochem Cell Biol. 72(11-12): 483-8.
2. Naik RR, et al. (2002) Biomimetic synthesis and patterning of silver nanoparticles. Nat Mater. 1(3): 169-72.
3. Djeu JY, et al. (2009) Clusterin and chemoresistance. Adv Cancer Res. 105: 77-92.