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Clusterin / Apolipoprotein J / Apo-J / CLU Antibody, Rabbit PAb, Antigen Affinity Purified

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    Mouse CLU Antibody Product Information
    Immunogen:Recombinant Mouse Clusterin / Apolipoprotein J / Apo-J / CLU protein (Catalog#50485-M08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS
    Preparation:Produced in rabbits immunized with purified, recombinant Mouse Clusterin / Apolipoprotein J / Apo-J / CLU (rM Clusterin / Apolipoprotein J / Apo-J / CLU; Catalog#50485-M08H; NP_038520.2; Met 1-Glu 448). Clusterin / Apolipoprotein J / Apo-J / CLU specific IgG was purified by Mouse Clusterin / Apolipoprotein J / Apo-J / CLU affinity chromatography.
    Other CLU Antibody Products
    Clusterin/Apolipoprotein J/Apo-J Background

    Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others.

    Mouse Clusterin/Apolipoprotein J/Apo-J References
  • Silkensen JR, et al. (1994) The role of clusterin in tissue injury. Biochem Cell Biol. 72(11-12): 483-8.
  • Naik RR, et al. (2002) Biomimetic synthesis and patterning of silver nanoparticles. Nat Mater. 1(3): 169-72.
  • Djeu JY, et al. (2009) Clusterin and chemoresistance. Adv Cancer Res. 105: 77-92.
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    Catalog: 50485-RP02-200
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    Datasheet & Documentation

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"