Chordin-Like 1 / CHRDL1 Protein

Chordin-Like 1 / CHRDL1 Products

Chordin-Like 1 / CHRDL1 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
Chordin-Like 1/CHRDL1	Human	Chordin-Like 1/CHRDL1 Protein, Recombinant	10866-H08H

Chordin-Like 1 / CHRDL1 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat No
Chordin-Like 1/CHRDL1	Human	Homo sapiens Chordin-Like 1/CHRDL1 cDNA Clone	HG10866-M
Chordin-Like 1/CHRDL1	Mouse	Mouse Chordin-Like 1/CHRDL1 cDNA gene Clone / ORF gene clone	MG50868-G

Chordin-Like 1 / CHRDL1 Related Areas

Cancer>>Growth Factor & Receptor>>TGF-beta Superfamily>>BMP Family>>Chordin-Like 1/CHRDL1

Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>>BMP Family>>Chordin-Like 1/CHRDL1

Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>>TGF-beta Superfamily Modulators>>Chordin-Like 1/CHRDL1

Chordin-Like 1 / CHRDL1 Alternative Names

CHRDL1, RP6-141H5.1, CHL, NRLN1, VOPT, dA141H5.1, neuralin-1, neurogenesin-1, ventroptin [Homo sapiens]

Chrdl1, RP23-346N16.1, BB139951, CHL, CHL1, Nrln1, VOPT, neuralin 1, neuralin-1, neurogenesin-1,  ventroptin,  ventroptin-alpha, ventroptin-beta,, verntroptin-beta [Mus musculus]

Chordin-Like 1 / CHRDL1 Background

Cordin-like 1 (CHRDL1) is an antagonist of bone morphogenetic protein 4. It may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Cordin-like 1 (CHRDL1) is an inhibitor of the bone morphogenetic proteins (BMPs) that have functions in inducing ectopic bone formation. CHRDL1 acheves its inhibiting ability through affecting the osteogenic differentiation of MC3T3-E1 cells. Besides its function as an antagonist, CHRDL1 enhanced the proliferation of human mesenchymal stem cells in a BMP2-independent manner.

Chordin-Like 1 / CHRDL1 Related Studies

1. Fernandes H, et al. (2010) Effect of chordin-like 1 on MC3T3-E1 and human mesenchymal stem cells. Cells Tissues Organs. 191 (6): 443-52.
2. Larman BW, et al. (2009) Chordin-like 1 and twisted gastrulation 1 regulate BMP signaling following kidney injury. J Am Soc Nephrol. 20 (5): 1020-31.
3. Kane R, et al. (2008) Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol Vis. 14: 1138-48.