CD52 Protein, Mouse, Recombinant (Fc Tag)

Cat: 50721-M02H
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All CD52 Reagents
CRO Services
Product recommended

All CD52 Reagents
CD52 Protein, Mouse, Recombinant (Fc Tag) Product Information
Purity
> 95 % as determined by SDS-PAGE.
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Activity
Testing in progress
Protein Construction
A DNA sequence encoding the mouse Cd52 (NP_038734.1) (Met1-Lys46) was expressed with the Fc region of human IgG1 at the C-terminus.
Expressed Host
HEK293 Cells
Species
Mouse
Predicted N Terminal
Gly 24
Molecule Mass
The recombinant mouse Cd52 consists 261 amino acids and predicts a molecular mass of 29 kDa.
Formulation
Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
2. Please contact us for any concerns or special requirements.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -70℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
CD52 Protein, Mouse, Recombinant (Fc Tag) in SDS-PAGE
Mouse CD52 / CDW52 Protein 11865
CD52 Protein, Mouse, Recombinant (Fc Tag) Alternative Names
AI463198 Protein, Mouse;B7 Protein, Mouse;B7-Ag Protein, Mouse;CAMPATH-1 Protein, Mouse;CLS1 Protein, Mouse;MB7 Protein, Mouse
CD52 Background Information

CD52 / CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52 / CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Full Name
CD52 molecule
References
  • Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.
  • Other CD52 Proteins

    Rat CD52 Proteins

    Product Name Cat.No.
    CD52 Protein, Rat, Recombinant (Fc Tag) 80298-R02H

    Human CD52 Proteins

    Product Name Cat.No.
    CD52 Protein, Human, Recombinant (Fc Tag) 15105-H02H
    info info
    添加购物车成功! 添加购物车失败!