Anti-Carboxypeptidase B1 Antibody

Cat: 50386-RP02
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Anti-Carboxypeptidase B1 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-Carboxypeptidase B1 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Mouse
Specificity
Mouse Carboxypeptidase B1
Immunogen
Recombinant Mouse CPB1 protein (Catalog#50386-M08H)
Preparation
Produced in rabbits immunized with purified, recombinant Mouse CPB1 (rM CPB1; Catalog#50386-M08H; NP_083982.1; Met 1-Tyr 415). CPB1 specific IgG was purified by mouse CPB1 affinity chromatography .
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Carboxypeptidase B1 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-Carboxypeptidase B1 Antibody Alternative Names
Anti-0910001A18Rik Antibody;Anti-1810063F02Rik Antibody;Anti-2210008M23Rik Antibody;Anti-AI504870 Antibody
Carboxypeptidase B1 Background Information

Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 307-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.

Full Name
carboxypeptidase B1 (tissue)
References
  • Yamamoto, K.K. et al., 1992, J. Biol. Chem. 267: 2575-2581.
  • Pezzilli, R. et al., 1994, Digestion. 55: 73-77.
  • Barbosa Pereira, P.J. et al., 2002, J. Mol. Biol. 321: 537-547.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-Carboxypeptidase B1 Antibody Rabbit Monoclonal ELISA(Cap) 50386-R001
    Anti-Carboxypeptidase B1 Antibody Rabbit Polyclonal ELISA 50386-RP01
    Anti-Carboxypeptidase B1 Antibody Rabbit Monoclonal ELISA(Det) 50386-R008
    Anti-Carboxypeptidase B1 Antibody Rabbit Monoclonal ELISA 50386-R117
    Anti-Carboxypeptidase B1 Antibody Rabbit Polyclonal ELISA 10501-RP01
    Anti-Carboxypeptidase B1 Antibody Rabbit Monoclonal ELISA,IHC-P 10501-R329
    Anti-Carboxypeptidase B1 Antibody Mouse Monoclonal ELISA,ELISA(Cap) 10501-MM06
    Anti-Carboxypeptidase B1 Antibody Mouse Monoclonal IHC-P 10501-MM07
    Anti-Carboxypeptidase B1 Antibody Rabbit Monoclonal ELISA(Det) 10501-R108
    Anti-Carboxypeptidase B1 Antibody Rabbit Polyclonal ELISA 10501-RP02
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