|Recombinant Human CPA2 protein (Catalog#10499-H08H)|
|0.2 μm filtered solution in PBS with 5% trehalose|
|This antibody was obtained from a rabbit immunized with purified, recombinant Human CPA2 (rh CPA2; Catalog#10499-H08H; NP_001859.1; Met 1-Tyr 417).|
No cross-reactivity in ELISA with
Human CPA1 / Carboxypeptidase A1
Human CPE / Carboxypeptidase E
Human Carboxypeptidase B1 / CPB1 / PCPB
ELISA: 0.1-0.2 μg/mL
This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CPA2. The detection limit for Human CPA2 is 0.00975 ng/well.
Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties.