**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-CA14 rabbit polyclonal antibody at 1:500 dilution
Lane A: 293T Membrane LysateLysates/proteins at 20 μg per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique.
Performed under reducing conditions.Predicted band size:38 kDa
Observed band size:38 kDa
(We are unsure as to the identity of these extra bands.)
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. CAXIV is a member of CA family that showed an overall similarity of 29–46% to other active CA isozymes. The highest percentage similarity was with a transmembrane CA isoform, CAXII. The CAXIV was found high concentrations in human heart, brain, liver, and skeletal muscle but lower in the colon, small intestine, urinary bladder, and kidney. No CAXIV mRNA was seen in the salivary gland and pancreas. CAXIV is a likely candidate for the extracellular CA postulated to have an important role in modulating excitatory synaptic transmission in brain.
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Polyclonal||WB,ELISA||50013-RP01|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Monoclonal||ELISA||50013-R033|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Monoclonal||ELISA,IHC-P,ICC/IF,IF||10458-R515|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Polyclonal||WB,ELISA,IHC-P,IP||10458-T60|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Monoclonal||WB,ELISA||10458-R004|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Monoclonal||ELISA(Cap)||10458-R110|
|Anti-Carbonic Anhydrase XIV Antibody||Rabbit||Polyclonal||ELISA||10458-RP01|