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Carbonic Anhydrase XII / Car12 Antibody, Rabbit PAb

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    Mouse CA12 Antibody Product Information
    Immunogen:Recombinant Mouse Ca12 protein (Catalog#50014-M08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Mouse Ca12 (rM Ca12; Catalog#50014-M08H; NP_848483.2; Met 1-Ser 301). Total IgG was purified by Protein A affinity chromatography.
    Other CA12 Antibody Products
    Reactivity: Human  
    Application: FCM  
    • Slide 1
    10617-MM07-P-25
    10617-MM07-P-100
    25 Test 
    100 Tests 
    Add to Cart
    Reactivity: Human  
    Application: IF  ICC/IF  
    • Slide 1
    10617-MM04-50
    10617-MM04-200
    10617-MM04-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      10617-MM08-50
      10617-MM08-200
      10617-MM08-100
      10617-MM08-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10617-MM11-F-25
      10617-MM11-F-100
      25 Test 
      100 Tests 
      Add to Cart
      Reactivity: Human  
      Application: FCM  
      • Slide 1
      10617-MM11-50
      10617-MM11-200
      10617-MM11-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: WB  IHC-P  
      • Slide 1
      • Slide 1
      • Slide 1
      • Slide 1
      10617-RP02-50
      10617-RP02-200
      10617-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: 
        10617-MM01-50
        10617-MM01-200
        10617-MM01-100
        10617-MM01-1
        50 µg 
        200 µg 
        100 µg 
        1 mg 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        10617-MM11-P-25
        10617-MM11-P-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: FCM  
        • Slide 1
        • Slide 1
        10617-MM07-F-25
        10617-MM07-F-100
        25 Test 
        100 Tests 
        Add to Cart
        Reactivity: Human  
        Application: FCM  IF  ICC/IF  
        • Slide 1
        • Slide 1
        10617-MM07-50
        10617-MM07-200
        10617-MM07-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Mouse  
        Application: ELISA  
          50014-R001-50
          50014-R001-100
          50 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  IHC-P  
          • Slide 1
          50014-RP02-50
          50014-RP02-200
          50014-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Mouse  
          Application: ELISA  
            10504-R003-50
            10504-R003-100
            50 µg 
            100 µg 
            Add to Cart
            Reactivity: Mouse  
            Application: ELISA  IHC-P  
            • Slide 1
            • Slide 1
            50014-R012-50
            50014-R012-100
            50 µg 
            100 µg 
            Add to Cart
            Carbonic Anhydrase XII Background

            Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CA12, also known as Car12 and carbonic anhydrase XII, is a type I  membrane enzyme of an N-terminal extracellular catalytic domain, a membrane-spanning α-helix, and a small intracellular C-terminal domain. It is highly expressed in colon, kidney, prostate, intestine and activated lymphocytes and moderately expressed in pancreas, ovary, and testis. Overexpression of the CA12 is observed in certain human cancers and is used as a tumor marker. rmCA12 corresponds to the extracellular domain and has both carbonic anhydrase activity and esterase activity.

            Mouse Carbonic Anhydrase XII References
          • Sahin, U. et al., 1996, Proc. Natl. Acad. Sci. U.S.A. 92 (25): 11810–11813.
          • Ivanov, S.V. et al., 1998, Proc. Natl. Acad. Sci. USA 95:12596 - 12601.
          • Strausberg, R.L. et al., 2002, Proc. Natl. Acad. Sci. USA 99:16899 - 16903.
          • Liao, S.Y. et al., 2003, J. Med. Genet. 40:257 - 262.
          • Supuran, C. T. et al., 2008, Curr Pharm Des. 14 (7): 601-602.
          • Elleuche, S. et al., 2009, Curr Genet. 55 (2): 211-222.
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            Catalog: 50014-RP01-100
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            Datasheet & Documentation

            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"