Anti-Carbonic Anhydrase X Antibody (PE) (Mouse Monoclonal antibody) General Information
Anti-Carbonic Anhydrase X Antibody (PE)
Reacts with: Human
Human Carbonic Anhydrase X
Recombinant Human Carbonic Anhydrase X / CA10 protein (Catalog#10687-H08H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carbonic Anhydrase X / CA10 (rh Carbonic Anhydrase X / CA10; Catalog#10687-H08H; NP_001076002.1; Met1-Asn300) and conjugated with PE under optimum conditions, the unreacted PE was removed.
Monoclonal Mouse IgG3 Clone #03
Aqueous solution containing 0.5% BSA and 0.09% sodium azide
10 μl/Test, 0.1 mg/ml
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
Anti-Carbonic Anhydrase X Antibody (PE) (Mouse Monoclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-Carbonic Anhydrase X Antibody (PE) (Mouse Monoclonal antibody) Images
Flow cytometric analysis of Human CA10 (CARPX) expression in HL60 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with PE Mouse anti-Human CA10 (CARPX). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Anti-Carbonic Anhydrase X Antibody (PE) Alternative Names
Anti-CA-RPX Antibody;Anti-CA10 Antibody;Anti-CARPX Antibody;Anti-HUCEP-15 Antibody
Carbonic Anhydrase X Background Information
Carbonic anhydrase X, also called carbonic anhydrase - related protein X (CARPX) and CA10, belongs to the CA family of zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide in various biological processes such as respiration, renal tubular acidification and bone resorption. The secreted protein CARPX without CA activity (hydration of CO2) is identified as an acatalytic member of the alpha-carbonic anhydrase subgroup. CARP X expression is detected in the adult total brain and almost all parts of the central nervous system, but not in the fetal brain. Accordingly, CARP X is suggested to play a role in the development of central nervous system, especially the brain. The same CARP X protein are encoded by multiple transcript variants of this gene.
carbonic anhydrase X
Okamoto, N. et al., 2001, Biochim. Biophys. Acta 1518:311-316. Taniuchi, K. et al., Neuroscience 112: 93-99. Supuran, C.T. et al., 2003, Med. Res. Rev. 23: 146-189.