Anti-CA8 Antibody

Cat: 10469-MM09
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Anti-CA8 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-CA8 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human CA8
No cross-reactivity in ELISA with E.coli cell lysate
Recombinant Human Carbonic Anhydrase VIII / CA8 protein (Catalog#10469-H08E)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Carbonic Anhydrase VIII / CA8 (rh Carbonic Anhydrase VIII / CA8; Catalog#10469-H08E; NP_004047.3; Met 1-Gln 290). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG2a Clone #1G5G12
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CA8 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-CA8 Antibody Alternative Names
Anti-CA-VIII Antibody;Anti-CALS Antibody;Anti-CAMRQ3 Antibody;Anti-CARP Antibody;Anti-MGC120502 Antibody;Anti-MGC99509 Antibody
CA8 Background Information

The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Full Name
carbonic anhydrase VIII
  • Lehtonen J, et al. (2004) Characterization of CA XIII, a Novel Member of the Carbonic Anhydrase Isozyme Family. The Journal of Biological Chemistry. 279: 2719-27.
  • Lindskog S. (1997) Structure and mechanism of carbonic anhydrase. Pharmacology & Therapeutics. 74(1):1-20.
  • Miyaji E, et al. (2003) Overexpression of carbonic anhydrase-related protein VIII in human colorectal cancer. The Journal of Pathology. 201(1): 37-45.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-CA8 Antibody Rabbit Polyclonal ELISA 50767-RP01
    Anti-CA8 Antibody Rabbit Polyclonal WB,ELISA,IHC-P,IP 50767-T60
    Anti-CA8 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 50767-R001
    Anti-CA8 Antibody Rabbit Monoclonal WB,IP 50767-R005
    Anti-CA8 Antibody Rabbit Monoclonal ELISA(Cap) 50767-R057
    Anti-CA8 Antibody Rabbit Polyclonal ELISA 10469-RP01
    Anti-CA8 Antibody Rabbit Polyclonal WB,ELISA,IP 10469-RP02
    Anti-CA8 Antibody Rabbit Monoclonal WB,IP 10469-R008
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