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Carbonic Anhydrase IX Protein & Antibody (CA IX, CA9)

Carbonic anhydrase IX

Carbonic Anhydrase IX Products

Carbonic Anhydrase IX Protein, Recombinant

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Carbonic Anhydrase IX Human Carbonic Anhydrase IX/Fc Protein, Recombinant 10107-H02H
Carbonic Anhydrase IX Human Carbonic Anhydrase IX Protein, Recombinant 10107-H08H
Carbonic Anhydrase IX Mouse Carbonic Anhydrase IX Protein, Recombinant 50660-M08H
Carbonic Anhydrase IX Canine CAIX / CA9 Protein, Recombinant 70028-D02H
Carbonic Anhydrase IX Canine CAIX / CA9 Protein, Recombinant 70028-D08H

  10107-H02H:  The specific activity is > 50 pmoles/min/µg. Measured by its esterase activity. The specific activity is measured with 1 mM 4-Nitrophenyl acetate and 1 μg enzyme at 400 nm in 100 µL of 12.5 mM Tris, 75 mM NaCl, pH 7.5.

  10107-H08H:  The specific activity is > 30 pmoles/min/µg. Measured by its esterase activity. The specific activity is measured with 1 mM 4-Nitrophenyl acetate and 2.5 µg enzyme at 400 nm in 100 μL of 12.5 mM Tris, 75 mM NaCl, pH 7.5.

  50660-M08H:  The specific activity is > 100 pmoles/min/µg. Measured by its esterase activity.

Carbonic Anhydrase IX Antibody

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
Carbonic Anhydrase IX
WB, ELISA Rabbit Monoclonal Antibody 10107-R003
Human
Carbonic Anhydrase IX
WB, ELISA, IHC-P Carbonic Anhydrase IX / CA9 Antibody 10107-R005
Human
Carbonic Anhydrase IX
WB, ELISA, IHC-P Carbonic Anhydrase IX / CA9 Antibody 10107-R036
Human
Carbonic Anhydrase IX
ELISA Rabbit Polyclonal Antibody 10107-RP01
Human
Carbonic Anhydrase IX
WB, ELISA, IHC-P Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10107-RP02
Mouse
Carbonic Anhydrase IX
WB, ELISA, Carbonic Anhydrase IX / CAR9 Antibody 50660-RP01
Mouse
Carbonic Anhydrase IX
WB, ELISA Carbonic Anhydrase IX / CAR9 Antibody (Antigen Affinity Purified) 50660-RP02

Carbonic Anhydrase IX Related Areas

Cancer>>Cancer Biomarkers>>Carbonic Anhydrase IX

Enzyme>>Carbonic Anhydrase>>Carbonic Anhydrase IX

Carbonic Anhydrase IX Alternative Names

Carbonic Anhydrase IX, CAIX, CA9, MN [Homo sapiens]

Carbonic Anhydrase IX, CAIX, Carbonic Anhydrase 9, Car9, MN/CA9, RP23-195K8.9 [Mus musculus]

Carbonic Anhydrase IX Related Products

Protein Products

Molecule Species Description //For Detailed Info. and Price------CLICK!
Carbonic Anhydrase II Human Carbonic Anhydrase II Protein, Recombinant
Carbonic Anhydrase II Mouse Carbonic Anhydrase II Protein, Recombinant
Carbonic Anhydrase III Human Carbonic Anhydrase III Protein, Recombinant
Carbonic Anhydrase IV Human Carbonic Anhydrase IV Protein, Recombinant
Carbonic Anhydrase IV Mouse Carbonic Anhydrase IV Protein, Recombinant
Carbonic Anhydrase VII Human Carbonic Anhydrase VII Protein, Recombinant
Carbonic Anhydrase VIII Human Carbonic Anhydrase VIII Protein, Recombinant
Carbonic Anhydrase VIII Mouse Carbonic Anhydrase VIII Protein, Recombinant
Carbonic Anhydrase X Human Carbonic Anhydrase X/Fc Protein, Recombinant
Carbonic Anhydrase X Human Carbonic Anhydrase X Protein, Recombinant
Carbonic Anhydrase X Human Carbonic Anhydrase X Protein, Recombinant
Carbonic Anhydrase X Mouse Carbonic Anhydrase X Protein, Recombinant
Carbonic Anhydrase XII Human Carbonic Anhydrase XII Protein, Recombinant
Carbonic Anhydrase XII Mouse Carbonic Anhydrase XII Protein, Recombinant
Carbonic Anhydrase XIII Human Carbonic Anhydrase XIII Protein, Recombinant
Carbonic Anhydrase XIV Human Carbonic Anhydrase XIV Protein, Recombinant
Carbonic Anhydrase XIV Mouse Carbonic Anhydrase XIV Protein, Recombinant

Antibody Products

Molecule Application Description //For Detailed Info. and Price------CLICK!
Human
Carbonic Anhydrase X
WB, ELISA Mouse Monoclonal Antibody
Human
Carbonic Anhydrase XII
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified)
Mouse
Carbonic Anhydrase XII
WB, ELISA Carbonic Anhydrase XII Antibody, Rabbit PAb
Mouse
Carbonic Anhydrase XII
WB, ELISA Carbonic Anhydrase XII Antibody, Rabbit PAb (Antigen Affinity Purified)
Human
Carbonic Anhydrase XIV
WB, ELISA Carbonic Anhydrase XIV Antibody, Rabbit Mab
Human
Carbonic Anhydrase XIV
WB, ELISA Rabbit Polyclonal Antibody
Mouse
Carbonic Anhydrase XIV
WB, ELISA Carbonic Anhydrase XIV Antibody, Rabbit PAb
Mouse
Carbonic Anhydrase XIV
WB, ELISA Carbonic Anhydrase XIV Antibody, Rabbit PAb (Antigen Affinity Purified)

cDNA Clone Products

Molecule Species Description //For Detailed Info. and Price------CLICK!
Carbonic Anhydrase II Human Homo sapiens Carbonic Anhydrase II cDNA Clone(NM_000067.2)
Carbonic Anhydrase III Human Homo sapiens Carbonic Anhydrase III cDNA Clone(NM_005181.3)
Carbonic Anhydrase IV Human Homo sapiens Carbonic Anhydrase IV cDNA Clone(NM_000717.3)
Carbonic Anhydrase IV Mouse Mus musculus Carbonic Anhydrase IV cDNA Clone
Carbonic Anhydrase VA Human Homo sapiens Carbonic Anhydrase VA cDNA Clone(NM_001739.1)
Carbonic Anhydrase VIII Human Homo sapiens Carbonic Anhydrase VIII cDNA Clone(NM_004056.4)
Carbonic Anhydrase XII Human Homo sapiens Carbonic Anhydrase XII cDNA Clone
Carbonic Anhydrase XII Mouse Mus musculus Carbonic Anhydrase XII cDNA Clone
Carbonic Anhydrase XIII Human Homo sapiens Carbonic Anhydrase XIII cDNA Clone(NM_198584.2)
Carbonic Anhydrase XIV Human Homo sapiens Carbonic Anhydrase XIV cDNA Clone(NM_012113.1)
Carbonic Anhydrase XIV Mouse Mus musculus Carbonic Anhydrase XIV cDNA Clone

Carbonic Anhydrase IX Background

Carbonic anhydrases IX (CA IX), also known as membrane antigen MN or CA9, is a member of the carbonic anhydrase (CA) family and may be involved in cell proliferation and cellular transformation. CAs are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide (H2O + CO2 = H+ + HCO3–) and thus participate in a variety of biological and physical processes. CA IX protein is expressed primarily in carcinoma cells lines, and the expression is cell density dependent and has been shown to be strongly induced by hypoxia, accordingly facilitates adaptation of tumor cells to hypoxic conditions. It is involved in tumorigenesis through many pathways, such as pH regulation and cell adhesion control. CA IX is used as a marker of tumor hypoxia and as a new therapeutic target for many human carcinomas and cancers.

Carbonic Anhydrase IX Related Studies

  1. Loncaster JA, et al. (2001) Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix. Cancer Res. 61(17): 6394-9.
  2. Závada J, et al. (2003) Soluble form of carbonic anhydrase IX (CA IX) in the serum and urine of renal carcinoma patients. Br J Cancer. 89(6): 1067-71.
  3. Pan P, et al. (2006) Carbonic anhydrase gene expression in CA II-deficient (Car2-/-) and CA IX-deficient (Car9-/-) mice. J Physiol. 571(Pt 2): 319-27.
  4. Zhou GX, et al. (2010) Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and diagnostic potentials. Urology. 75(2): 257-61.

 

 

Carbonic Anhydrase IX (CA9) related areas, pathways, and other information