Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase)

Sino Biological provides a range of tools for Ca²⁺/calmodulin-dependent protein kinase (CaM kinase) related research, including recombinant proteins, antibodies, ELISA kits, and gene cDNA clones.

Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) Products

• CAMK1
• CAMK2B
• CAMKV
• CAMK1D / CKLiK
• CAMK2D
• CaMKK1
• CAMK1G
• CAMK2G
• CASK
• CAMK2A
• CAMK4
• PNCK

Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) Background

Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein making proteins phosphorylated. A change in intracellular free calcium (Ca²⁺) is a common signaling mechanism that modulates a wide array of physiological processes in most cells. Neuronal activity can lead to marked increases in the concentration of cytosolic calcium, which then functions as a second messenger that mediates a wide range of cellular responses. Calcium binds to calcium binding proteins (calmodulin/CaM) and stimulates the activity of a variety of enzymes, including CaM kinases referred to as CaM-kinases (CaMKs), such as CaMKI, CaMKII, CaMKIV and CaMKK, that can phosphorylate multiple downstream targets.

Calcium/Calmodulin-Dependent Protein Kinase (CaM Kinase) Related Studies

1. Wayman GA, et al. (2011) Analysis of CaM-kinase signaling in cells. Cell Calcium. 50(1): 1-8.
2. Celio MR, et al. (1981) Calcium-binding protein parvalbumin as a neuronal marker. J Nature. 293(5830): 300-2.
3. Ghosh A, et al. (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. J Science. 268(5208): 239-47.