All CXCL14 reagents are produced in house and quality controlled, including 39 CXCL14 Gene, 2 CXCL14 Protein, 2 CXCL14 qPCR. All CXCL14 reagents are ready to use.
Recombinant CXCL14 proteins are expressed by E. coli with fusion tags as Native.
CXCL14 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each CXCL14 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
CXCL14 is a CXC chemokine family that exhibits antimicrobial activity and contains an amphipathic cationic alpha-helical region in the C-terminus, a characteristic structure of antimicrobial peptides (AMPs). CXCL14 is involved in cell recruitment, migration, activation, and homing in liver diseases and have been shown to be upregulated during acute liver injury in animal models. The CXC chemokine ligand 14 (CXCL14) had been show highly expressed in tumor-associated stromal cells, promoting tumor cell growth, and invasion. The stimulation of dysregulated CXCL14 expression by P. gingivalis may help promote dysbiosis and the development of chronic periodontitis. The level of CXCL14 expression may be a valuable adjuvant parameter to predict the prognosis of patients with oral carcinoma and may be a potential therapeutic target.