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CXCL1

CXCL1 Protein & Antibody

CXCL1 Related Information

CXCL1N


CXCL1 gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of CXCL1 gene. A pseudogene of CXCL1 gene is found on chromosome 4. [provided by RefSeq, Jan 2012]

OMIM-Description for CXCL1N


Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.

CXCL1


Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene, GROα, KC, Neutrophil-activating protein 3 (NAP-3) and melanoma growth stimulating activity, alpha (MSGA-α). In humans, this protein is encoded by the CXCL1 gene.

CXCL1 Alternative Names

MGSA,CXCL1,FSP,GRO1,GROa,MGSA-a,NAP-3,SCYB1, [human]
KC,CXCL1,Fsp,gro,Gro1,Mgsa,N51,Scyb1, [mouse]

CXCL1 Related Products

CXCL1 Proteins

Product nameProduct name
Mouse CXCL1 / MGSA / NAP-3 ProteinHuman CXCL1 / MGSA / NAP-3 ProteinHuman CXCL1 / MGSA / NAP-3 Protein (His & NusA Tag)Human CXCL1 / MGSA / NAP-3 Protein (His & SUMO Tag)

CXCL1 Antibodies

Product nameProduct name

CXCL1 cDNA Clones

Product nameProduct name
Human CXCL1 Gene cDNA Clone (full-length ORF Clone)Human CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedHuman CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, His-taggedHuman CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedHuman CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedHuman CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-taggedMouse CXCL1 Gene cDNA Clone (full-length ORF Clone)Mouse CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedMouse CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, His-taggedMouse CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedMouse CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedMouse CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-taggedRat CXCL1 Gene cDNA Clone (full-length ORF Clone)Rat CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedRat CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, His-taggedRat CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedRat CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedRat CXCL1 Gene cDNA Clone (full-length ORF Clone), expression ready, HA-tagged

CXCL1 ELISA

Product nameProduct name
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"