Anti-C-Reactive Protein Antibody

Cat: 80041-RP02
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Anti-C-Reactive Protein Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-C-Reactive Protein Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Rat
Specificity
Rat C-Reactive Protein
Immunogen
Recombinant Rat CRP / C-Reactive Protein protein (Catalog#80041-R08H)
Preparation
Produced in rabbits immunized with purified, recombinant Rat CRP / C-Reactive Protein (rR CRP / C-Reactive Protein; Catalog#80041-R08H; NP_058792.1; Met 1-Ser 230). CRP / C-Reactive Protein specific IgG was purified by Rat CRP / C-Reactive Protein affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-C-Reactive Protein Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

C-Reactive Protein Background Information

C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.

Full Name
C-reactive protein, pentraxin-related
References
  • Pepys MB. et al., 2003, J Clin Invest. 111 (12): 1805-12.
  • Thompson D. et al., 1999, Structure. 7(2): 169-77.
  • Product Description Host Clonality Application Catalog# (PDF)
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    Anti-C-Reactive Protein Antibody Rabbit Polyclonal WB,ELISA,IHC-P 11250-RP02
    Anti-C-Reactive Protein Antibody Mouse Monoclonal ELISA(Cap) 11250-MM07T
    Anti-C-Reactive Protein Antibody Rabbit Monoclonal ELISA(Det) 11250-R106
    Anti-C-Reactive Protein Antibody Rabbit Monoclonal ELISA 11250-R069
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