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CRP / C-reactive Protein Antibody, Rabbit PAb

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    Mouse CRP Antibody Product Information
    Immunogen:Recombinant Mouse CRP protein (Catalog#50409-M08H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Mouse CRP (rM CRP; Catalog#50409-M08H; NP_031794.3; Met 1-Ser 225). Total IgG was purified by Protein A affinity chromatography .
    Other CRP Antibody Products
    C-Reactive Protein/CRP Background

    C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monitor many human diseases. However, CRP is likely to have important host defence, scavenging and metabolic functions through its capacity for calcium-dependent binding to exogenous and autologous molecules containing phosphocholine (PC) and then activating the classical complement pathway. CRP may also have pathogenic effects and the recent discovery of a prognostic association between increased CRP production and coronary atherothrombotic events is of particular interest.

    Mouse C-Reactive Protein/CRP References
  • Pepys MB. et al., 2003, J Clin Invest. 111 (12): 1805-12.
  • Thompson D. et al., 1999, Structure. 7(2): 169-77.
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    Catalog: 50409-RP01-400
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    Datasheet & Documentation

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