Quick Order

CPN1  Protein, Antibody, ELISA Kit, cDNA Clone

CPN1 Related Area

CPN1 Related Pathways

    CPN1 Summary & Protein Information

    CPN1 Background

    Catalytic activity: Release of a C-terminal basic amino acid, preferentially lysine.
    Cofactor: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; ; Note=Binds 1 zinc ion per subunit.;
    Subunit structure: Tetramer of two catalytic chains and two glycosylated inactive chains. {ECO:0000269|PubMed:17157876}.
    Subcellular location: Secreted, extracellular space.
    Tissue specificity: Synthesized in the liver and secreted in plasma.
    Involvement in disease: DISEASE: Carboxypeptidase N deficiency (CPND) [MIM:212070]: Patients affected present some combination of angioedema or chronic urticaria, as well as hay fever or asthma, and have also slightly depressed serum carboxy peptidase N, suggestive of autosomal recessive inheritance of this disorder. {ECO:0000269|PubMed:12560874}. Note=The disease is caused by mutations affecting the gene represented in this entry.
    Sequence similarity: Belongs to the peptidase M14 family. {ECO:0000305}.
    General information above from UniProt

    CPN1 Alternative Name

    CPN,SCPN, [homo-sapiens]
    CPN,0610011F20Rik, [mus-musculus]

    CPN1 Related Studies

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"