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Rat Contactin 3 / CNTN3 Protein (Fc Tag)
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Rat Contactin 3 / CNTN3 Protein (Fc Tag) PDF Download

Catalog   Size (Price) Quantity In Stock Operation
80316-R02H  
YES   
 

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Contactin 3 (plasmacytoma associated) Protein Datasheet

 

CNTN3 / Contactin-3 Protein Price Inquiry ( Available Sizes )

CNTN3 / Contactin-3 Protein Product Information

Synonym : CNTN3
Protein Construction:

A DNA sequence encoding the rat CNTN3 (Met1-Gly1001) was expressed with the Fc region of human IgG1 at the C-terminus.

Source: Rat
Expression Host: Human Cells

CNTN3 / Contactin-3 Protein QC Testing

Purity: > 85% as determined by SDS-PAGE SDS-PAGE:
SDS-PAGE

CNTN3 / Contactin-3 protein

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal: Glu 20
Molecular Mass:

The recombinant rat CNTN3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 1224 amino acids and has a predicted molecular mass of 134.8 kDa. The apparent molecular mass of the protein is approximately 135 kDa in SDS-PAGE under reducing conditions.

Formulation: Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
  2. Please contact us for any concerns or special requirements.

CNTN3 / Contactin-3 Protein Usage Guide

Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

CNTN3 / Contactin-3 Protein Related Products & Topics

Related Areas:

Immunology>>Adhesion Molecule>> Cell Adhesion Molecule (IgSF CAM) >>Contactin 3/CNTN3

Proteins:

Molecule Species Description //For Detailed Info. and Price------CLICK! Cat. No
Contactin 3/CNTN3 Human Contactin 3/CNTN3/Fc Protein, Recombinant 10174-H02H
Contactin 3/CNTN3 Human Contactin 3/CNTN3 Protein, Recombinant 10174-H08H
Contactin 3/CNTN3 Mouse CNTN3 / Contactin-3 Protein, Recombinant 51007-M08H
Contactin 3/CNTN3 Rat CNTN3 / Contactin-3 Protein, Recombinant 80316-R02H
Contactin 3/CNTN3 Rat CNTN3 / Contactin-3 Protein, Recombinant 80316-R08H

Antibodies:

Molecule Application Description //For Detailed Info. and Price------CLICK! Cat. No
Human
Contactin 3/CNTN3
WB, ELISA Mouse Monoclonal Antibody 10174-MM01
Human
Contactin 3/CNTN3
WB, ELISA Contactin 3/CNTN3 Antibody, Rabbit MAb 10174-R006
Human
Contactin 3/CNTN3
WB, ELISA Rabbit Polyclonal Antibody 10174-RP02
Human
Contactin 3/CNTN3
WB, ELISA Rabbit Polyclonal Antibody (Antigen Affinity Purified) 10174-RP03

CNTN3 / Contactin-3 Protein Description

The brain-derived axon-associated cell adhesion molecule BIG-1, also known as CNTN3 or PANG (plasmacytoma-associated neuronal glycoprotein) ,belongs to the contactin family consisting of six members (CNTN1/F3, CNTN2/TAG-1, CNTN3/BIG-1, CNTN4/BIG-2, CNTN5/NB-2 and CNTN6/NB-3). CNTN3 is a member of the immunoglobulin (Ig)superfamily with six Ig-like domains, four fibronectin type I II-like repeats, and a GPI-anchoring domain. The expression pattern of CNTN3 is developmentally regulated with the highest level in the adult brain , and restricted to subsets of neurons such as Purkinje cells of the cerebellum, granule cells of the dentate gyrus, and neurons in the superficial layers of the cerebral cortex. It has been suggested that BIG-1 has a neurite outgrowth-promoting activity ,and play an important role in the formation and maintenance of specific neuronal networks in the brain together with other contactin members.

References

  1. Yoshihara Y. et al., 1994, Neuron. 13: 415-26.
  2. Yoshihara Y. et al., 1995, J Neurobiol. 28: 51-69.
  3. Connelly M.A., et al., 1994, Proc Natl Acad Sci. 91: 1337-41.
  4. Mock BA. et al., 1996, Genomics. 34: 226-8.
 
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"