CNPY4 belongs to the canopy family. CNPY4 interacts with toll-like receptor 4 (TLR4) and plays a role in the regulation of the cell surface expression of TLR4. Toll-like receptors (TLRs) recognize microbial products and induce immune responses. Lipopolysaccharide is recognized by the receptor complex consisting of TLR4 and MD-2. As CNPY4, PRAT4B also regulates cell surface expression of TLR4. PRAT4B has a signal peptide followed by a mature peptide. It is associated with the hypoglycosylated, immature form of TLR4 but not with MD-2 or TLR2.
CNPY4 ELISA Pair sets
CNPY4 cDNA Clones
PSEC0237, PRAT4B, PRotein Associated with Tlr4, protein canopy homolog 4 [Homo sapiens]
2610019P18Rik, protein associated with Tlr4, protein canopy homolog 4 [Mus musculus]
Belongs to the canopy family.
Interacts with TLR4
General information above from UniProt
CNPY4 plays a role in the regulation of the cell surface expression of TLR4.
- CNPY4 regulates cell surface expression of TLR4