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CNPY4

CNPY4 belongs to the canopy family. CNPY4 interacts with toll-like receptor 4 (TLR4) and plays a role in the regulation of the cell surface expression of TLR4. Toll-like receptors (TLRs) recognize microbial products and induce immune responses. Lipopolysaccharide is recognized by the receptor complex consisting of TLR4 and MD-2. As CNPY4, PRAT4B also regulates cell surface expression of TLR4. PRAT4B has a signal peptide followed by a mature peptide. It is associated with the hypoglycosylated, immature form of TLR4 but not with MD-2 or TLR2.

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Contents

CNPY4 Related Products

CNPY4 Proteins

CNPY4 Antibodies

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CNPY4 ELISA Pair sets

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CNPY4 cDNA Clones

CNPY4 Related Areas

CNPY4 Related Pathways

CNPY4 Alternative Names

PSEC0237, PRAT4B, PRotein Associated with Tlr4, protein canopy homolog 4 [Homo sapiens]

2610019P18Rik, protein associated with Tlr4, protein canopy homolog 4 [Mus musculus]

Summaries for CNPY4

Human CNPY4 Protein General Information

 

Protein names

CNPY4

Sequence length

248 AA.

Domain

Signal

Sequence similarities:

Belongs to the canopy family.
Contains 1 saposin B-type domain.

Subunit structure

Interacts with TLR4

Subcellular location: Secreted

General information above from UniProt

Function for CNPY4 Protein

UniProtKB:

CNPY4 plays a role in the regulation of the cell surface expression of TLR4.

Genatlas:

  • CNPY4 regulates cell surface expression of TLR4

Homology for human CNPY4

Phenotype Information for CNPY4

Drugs for CNPY4

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