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Canopy 4 homolog (zebrafish) Protein Datasheet
CNPY4 Protein Price Inquiry ( Available Sizes )
CNPY4 Protein Product Information
A DNA sequence encoding the human CNPY4 (Q8N129) (Met1-Leu248) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
CNPY4 Protein QC Testing
|Purity:||> 85% as determined by SDS-PAGE||SDS-PAGE:
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Gly 22|
The recombinant human CNPY4 consists of 238 amino acids and predicts a molecular mass of 27.4 KDa. It migrates as an approximately 32 KDa band in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH 7.4.
CNPY4 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
CNPY4 Protein Related Products & Topics
CNPY4 Protein Description
CNPY4 is a member of the canopy family. CNPY4 interacts with toll-like receptor 4 (TLR4) and plays a role in the regulation of the cell surface expression of TLR4. Toll-like receptors (TLRs) recognize microbial products and induce immune responses. As CNPY4, PRAT4B also regulates cell surface expression of TLR4. PRAT4B has a signal peptide followed by a mature peptide. It is associated with the hypoglycosylated, immature form of TLR4. Lipopolysaccharide is recognized by the receptor complex consisting of TLR4 and MD-2.
- Stelzl U. et al., 2005, Cell. 122 (6): 957-68.
- Hocking JC. et al., 2010, Mech Dev. 127 (1-2): 36-48.
- Hart BE. et al., 2012, J Biol Chem. 287 (20): 16550-62.