Anti-CNDP2 Antibody (Rabbit Monoclonal antibody) General Information
Reacts with: Mouse
No cross-reactivity in ELISA with
Recombinant Mouse CNDP2 protein (Catalog#50246-M08B)
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CNDP2 (rM CNDP2; Catalog#50246-M08B; NP_075638.2; Met 1-Asn 475).
Monoclonal Rabbit IgG Clone #001
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-CNDP2 Antibody (Rabbit Monoclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-CNDP2 Antibody (Rabbit Monoclonal antibody) Images
Anti-CNDP2 rabbit monoclonal antibody at 1:500 dilution
Lane A: A431 Whole Cell Lysate
Lysates/proteins at 30 μg per lane.
Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.
Developed using the Odyssey technique.
Performed under reducing conditions.
Predicted band size:53 kDa
Observed band size:53 kDa
Anti-CNDP2 Antibody Alternative Names
Anti-0610010E05Rik Antibody;Anti-C76600 Antibody;Anti-Cn2 Antibody;Anti-Dip-2 Antibody;Anti-Pep-1 Antibody;Anti-Pep1 Antibody
CNDP2 Background Information
Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to the peptidase M20A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. It may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform 1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform 2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis.
CNDP dipeptidase 2 (metallopeptidase M20 family)
Bakker,SJ. et al., 2008, Diabetes 57 (12):e16; author reply e17. Wanic, K. et al., 2008, Diabetes 57 (9): 2547-51. McDonough,CW. et al., 2009, Hum Genet 126 (2): 265-75. Kaur,H. et al., 2009, J Biol Chem. 284 (21):14493-502.