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Human cytomegalovirus (HCMV) Glycoprotein B / gB Antibody, Rabbit MAb

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    CMV gB Antibody Product Information
    Immunogen:Recombinant Human CMV gB / Glycoprotein B protein (Catalog#10202-VCCH1)
    Clone ID:38
    Ig Type:Rabbit IgG
    Concentration:
    Endotoxin:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human CMV gB (Catalog#10202-VCCH1; AAA45920.1) extracellular domain (Met 1-Lys 700) linked with the cytoplasmic domain (Arg 777-Val 907).
    Other gB Antibody Products
    Reactivity: CMV  
    Application: ELISA  WB  
      10202-MM02-50
      10202-MM02-100
      50 µg 
      100 µg 
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      Reactivity: CMV  
      Application: ELISA  
        10202-RP02-50
        10202-RP02-100
        50 µg 
        100 µg 
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        Reactivity: CMV  
        Application: ELISA  
          10202-RP01-200
          10202-RP01-100
          200 µg 
          100 µg 
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          Glycoprotein B/CMV gB Background

          Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 907-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.

          CMV Glycoprotein B/CMV gB References
        • Lopper M,et al. (2002). Disulfide bond configuration of human cytomegalovirus glycoprotein B. J Virol. 76(12): 6073-82.
        • Isaacson MK, et al. (2009) Human cytomegalovirus glycoprotein B is required for virus entry and cell-to-cell spread but not for virion attachment, assembly, or egress. J Virol. 83(8): 3891-903.
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          Catalog: 10202-R038-50
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          Datasheet & Documentation

          All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
          Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"